SAB4503999

Anti-phospho-TIE2 (pTyr¹¹⁰⁸) antibody produced in rabbit

affinity isolated antibody

• 동의어(들): Anti-CD202B, Anti-GLC3E, Anti-TIE-2, Anti-VMCM, Anti-VMCM1
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: antigen 125 kDa
• 종 반응성: mouse, rat, human
• 농도: ~1 mg/mL
• 기술: ELISA: 1:10000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• NCBI 수납 번호: Q02763
• UniProt 수납 번호: Q02763
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: phosphorylation (pTyr1108)
• 유전자 정보: human ... TEK(7010)

설명

일반 설명

The TIE2 (TEK receptor tyrosine kinase) is also termed as TEK (tyrosine-protein kinase receptor). This gene is located on human chromosome 9p21.2. It is expressed in the Schlemm′s canal endothelial of the eye. TIE2 belongs to the receptor tyrosine kinases family.

면역원

The antiserum was produced against synthesized peptide derived from human TIE2 around the phosphorylation site of Tyr1108.

Immunogen Range: 1074-1123

생화학적/생리학적 작용

Tie-2 (TEK receptor tyrosine kinase) protein induces angiogenesis and supports endothelial cell survival, upon binding of angiopoietin-1 (an endothelial growth factor) to the receptor. This gene is necessary for Schlemm′s canal formation. This gene regulates vascular homeostasis by involving in auto or transphosphorylation. Tie-2 is essential for the growth of vascular structures during embryogenesis.

특징 및 장점

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물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable