ABE95

Anti-PRDM12 Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): PR domain zinc finger protein 12, PR domain-containing protein 12, arg methyltransferase, arginine methyltransferase, PR domain family
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: human, mouse
• 기술: immunocytochemistry: suitable; western blot: suitable
• NCBI 수납 번호: NP_067632
• UniProt 수납 번호: Q9H4Q4
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... PRDM12(59335)

설명

일반 설명

Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. The retinoblastoma protein-interacting zinc finger gene RIZ1 is a tumor suppressor gene and the founding member of the PR domain family. PRDM12 (PR domain zinc finger protein 12) also acts as a tumor suppressor and is linked to the pathogenesis of chronic myeloid leukemia. PRDM12 is also thought to play a role in transcriptional regulation.

면역원

KLH-conjugated linear peptide corresponding to human PRDM12.

애플리케이션

Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected PRDM12 in NIH/3T3 and A431 cells.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Histones

Use Anti-PRDM12 Antibody (Rabbit Polyclonal Antibody) validated in WB, ICC to detect PRDM12 also known as PR domain zinc finger protein 12, arginine methyltransferase.

품질

Evaluated by Western Blot in human liver tissue lysate.

Western Blot Analysis: 3 μg/mL of this antibody detected PRDM12 on 10 µg of human liver tissue lysate.

표적 설명

~37 kDa observed

물리적 형태

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
Human liver tissue lysate.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable