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Merck
모든 사진(2)

Key Documents

AB5905

Sigma-Aldrich

Anti-Vesicular Glutamate Transporter 1 Antibody

serum, Chemicon®

동의어(들):

VGLUT1, BNPI

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

guinea pig

Quality Level

항체 형태

serum

항체 생산 유형

primary antibodies

클론

polyclonal

종 반응성

rat

제조업체/상표

Chemicon®

기술

immunohistochemistry: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

타겟 번역 후 변형

unmodified

유전자 정보

일반 설명

Vesicular glutamate transporter 1 (VGLUT1) is encoded by the gene mapped to human chromosome 19q13. VGLUT1 is specifically expressed in neuronal cells in the brain. It is characterized with a conserved C-terminal dileucine-like motif and two polyproline domains distal to C- terminal end, including one that binds to endocytic BAR (Bin/Amphiphysin/Rvs) domain protein, endophilin.

특이성

Recognizes Vesicular Glutamate Transporter 1 (VGLUT1, BNPI {Brain specific Na+ dependent inorganic phosphate cotransporter}). The antiserum has been tested on tissue sections from the rat central nervous system (CNS) using immunofluorescence histochemistry. The antiserum mainly labels nerve fibers and terminals. VGLUT1 is an excellent marker for glutamatergic nerve terminals. The staining pattern for the staining obtained with the VGLUT1 antiserum corresponds to the pattern described using other antisera to VGLUT1 (Bellocchio et al., 1998; Fremeau et al., 2001; Fujiyama et al., 2001; Sakata-Haga et al., 2001; Tong et al., 2001; Kaneko et al. 2002; Varoqui et al., 2002). Preabsorption of the VGLUT1 antiserum with immunogen peptide eliminates all immunostaining.

면역원

Synthetic peptide from rat VGLUT1 protein with no overlap to VGLUT2. The immunogen is available as AG208.

애플리케이션

  • Tested Applications

    Immunocytochemistry Analysis: A 1:250 dilution from a representative lot detected Vesicular Glutamate Transporter 1 in rat E18 cortical cells.
  • Note: Actual optimal working dilutions must be determined by end user as specimens, and experimental conditions may vary with the end user

표적 설명

62 kDa

물리적 형태

Guinea pig Serum in 0.1% Sodium Azide.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1


시험 성적서(COA)

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