추천 제품
생물학적 소스
rabbit
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
종 반응성
human
기술
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... CX3CR1(1524)
일반 설명
C-X3-C motif chemokine receptor 1 (CX3CR1) is a transmembrane G-coupled chemokine receptor of its ligand, fractalkine. This receptor is expressed on epithelial cells, smooth muscle cells, microglia, monocytic cells and natural killer cells. The gene encoding CX3CR1 is localized on human chromosome 3p21.3 and has five exons.
면역원
Synthetic 19 amino acid peptide from 3rd extracellular domain of human CX3CR1. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Gibbon, Monkey (95%); Marmoset, Mouse, Panda (84%).
생화학적/생리학적 작용
C-X3-C motif chemokine receptor 1 (CX3CR1) may be linked to the development of macular degeneration. It also acts as a receptor aiding viral entry.
특징 및 장점
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물리적 형태
Solution in phosphate-buffered saline containing less than 0.1% sodium azide.
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Storage Class Code
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
CX3CR1 is an important surface molecule for respiratory syncytial virus infection in human airway epithelial cells.
The Journal of General Virology, 96(9), 2543-2556 (2015)
Fractalkine/CX3CR1 induces apoptosis resistance and proliferation through the activation of the AKT/NF-?B cascade in pancreatic cancer cells.
Cell Biochemistry and Function, 35(6), 315-326 (2017)
CX3CR1 polymorphisms and the risk of age-related macular degeneration.
International Journal of Clinical and Experimental Pathology, 8(8), 9592-9596 (2015)
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