AB2994

Anti-Phospho-Bid (Ser65) Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): BH3-interacting domain death agonist, p22 BID, BID
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: human
• 기술: western blot: suitable
• NCBI 수납 번호: NM_001196.2
• UniProt 수납 번호: P55957-2
• 배송 상태: wet ice
• 타겟 번역 후 변형: phosphorylation (pSer65)
• 유전자 정보: human ... BID(637)

설명

일반 설명

Bid is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. Bid induces ICE-like proteases and apoptosis. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the major proteolytic product p15 Bid translocates to mitochondria where it triggers cytochrome c release.

특이성

Other species have not been tested.

The antibody reacts with the 22 kDa phospho-Bid-S65 protein.

면역원

Epitope: Ser65

애플리케이션

Anti-Phospho-Bid (Ser65) Antibody detects level of Phospho-Bid (Ser65) & has been published & validated for use in WB.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

품질

Evaluated by Western Blot on Jurkat cell lysate treated with (+/-) insulin.

Western Blot Analysis:
A 1:100~500 dilution of this antibody detected phospho-Bid-S65 on jurkat cell lysate treated with (+/-) insulin.

표적 설명

22 kDa

물리적 형태

Antigen Affinity Purified

Purified in PBS with 0.09% NaN3.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
Western Blot:: Jurkat cell lysate

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable