AB2256

Anti-GABA B Receptor R1 Antibody

serum, from guinea pig

• 동의어(들): GABA-B receptor, GABA-B receptor 1, GABAB, subunit 1c, gamma-aminobutyric acid (GABA) B receptor 1, gamma-aminobutyric acid B receptor 1, seven transmembrane helix receptor
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: guinea pig
• Quality Level: 100
• 항체 형태: serum
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 종 반응성: mouse, human, rat
• 기술: immunohistochemistry: suitable; western blot: suitable
• NCBI 수납 번호: NP_112290.2
• UniProt 수납 번호: Q9Z0U4
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: mouse ... Gabbr1(54393)

설명

일반 설명

Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates 4 transcript variants.

특이성

Cat. # AB2256 recognizes GABA B Receptor R1 (GABA B R1)

Reactivity with other species has not been determined.

면역원

Epitope: C-Terminus
interaction w/ ATF4

Recombinant peptide (aa 972-991: PSEPPDRLSCDGSRVHLLYK)

애플리케이션

Detect GABA B Receptor R1 using this Anti-GABA B Receptor R1 Antibody validated for use in WB, IH.

Immunohistochemistry: Working dilution of 1:3,000 in free floating mouse brain tissue.

Research Category
Neuroscience

Research Sub Category
Neurotransmitters & Receptors

품질

Western Blotting: 1:1,000 dilution from a previous lot detected GABA B R1 on 10µg of rat brain lysate.

표적 설명

~100-105 kDa

물리적 형태

GST-Depleted Sera with 0.05% NaN3.

저장 및 안정성

Stable for 1 year at -20ºC from date of receipt.

분석 메모

Control
Rat brain lysates

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable