추천 제품
제품명
Anti-Aquaporin 4 Antibody, Chemicon®, from rabbit
생물학적 소스
rabbit
Quality Level
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
정제법
affinity chromatography
종 반응성
human, mouse, rat
제조업체/상표
Chemicon®
기술
western blot: suitable
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... AQP4(361)
일반 설명
The water-specific channel Aquaporin 4 is located in various tissues including the gastro intestinal tract, kidney and brain. It is an osmoreceptor which regulates body water balance and mediates water flow within the central nervous system. The localization of AQ4 to astrocyte endfeet makes it an excellent marker for astrocyte distal processes.
특이성
Recognizes Aquaporin 4.
The antibody has not yet been tested for cross-reactivity to other species. The immunogen shows 94% similarity to mouse, 88% to bovine, 86% to rabbit and 82% to human AQP4 (hAQP4).
면역원
Epitope: C-Terminus
Synthetic Linear Peptide
애플리케이션
Anti-Aquaporin 4 Antibody is an antibody against Aquaporin 4 for use in WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Ion Channels & Transporters
Ion Channels & Transporters
Western Blotting: 0.5-1 μg/mL using Chemiluminescence technique.
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
표적 설명
~34 kDa
결합
Replaces: AB3068
물리적 형태
ImmunoAffinity Purified
Purified in PBS with 0.05% NaN3
저장 및 안정성
Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
분석 메모
Control
Tested on adult rat brain lysate
Tested on adult rat brain lysate
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Loss of astrocyte polarization upon transient focal brain ischemia as a possible mechanism to counteract early edema formation.
Glia null
Evidence of a rudimentary colon in the elasmobranch, Leucoraja erinacea.
Development Genes and Evolution null
Loss of astrocyte polarity marks blood-brain barrier impairment during experimental autoimmune encephalomyelitis.
Acta neuropathologica null
Absence of glial ?-dystrobrevin causes abnormalities of the blood-brain barrier and progressive brain edema.
The Journal of Biological Chemistry null
Acta neuropathologica, 131(5), 753-773 (2016-03-05)
The homeostasis of the central nervous system is maintained by the blood-brain barrier (BBB). Angiopoietins (Ang-1/Ang-2) act as antagonizing molecules to regulate angiogenesis, vascular stability, vascular permeability and lymphatic integrity. However, the precise role of angiopoietin/Tie2 signaling at the BBB
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