AB15242

Anti-zDHHC8 Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): Zinc finger DHHC domain-containing protein 8, Zinc finger protein 378, membrane-associated DHHC8 zinc finger protein, zinc finger, DHHC domain containing 8, zinc finger, DHHC domain like containing 1, zinc finger, DHHC-type containing 8
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: rat, human
• 종 반응성(상동성에 의해 예측): horse, bovine, Xenopus, chicken, pig, chimpanzee, ape, opossum, mouse, dog
• 기술: western blot: suitable
• UniProt 수납 번호: Q9ULC8
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: chimpanzee ... Zdhhc8(458662) ; human ... ZDHHC8(29801)

설명

일반 설명

Six genes in the 1.5 Mb region of chromosome 22 deleted in DiGeorge/22q11 deletion syndrome–Mrpl40, Prodh, Slc25a1, Txnrd2, T10, and Zdhhc8–encode mitochondrial proteins. All six genes are expressed in the
brain, and maximal expression coincides with peak forebrain synaptogenesis shortly after birth. Furthermore, their protein products are associated with brain mitochondria, including those in synaptic terminals. Among the six, only Zddhc8 influences mitochondria-regulated apoptosis when overexpressed, and appears to interact biochemically with established mitochondrial proteins. Zdhhc8 has an apparent interaction with Uqcrc1, a component of mitochondrial complex III. The two proteins are coincidently expressed in pre-synaptic processes; however, Zdhhc8 is more frequently seen in glutamatergic terminals (1).

특이성

Cat. AB15242 recognizes the C-terminus of zDHHC8.

면역원

Epitope: C-Terminus

Syntheic linear peptide.

애플리케이션

Anti-zDHHC8 Antibody is an antibody against zDHHC8 for use in WB.

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

품질

Routinely evaluated by western blot in fetal human brain lysate.

표적 설명

~71 kDa

물리적 형태

ImmunoAffinity Purified

Purified in PBS with 0.05% NaN3

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.
Handling Recommendations: Prior to removing the cap, gently centrifuge the vial and gently mix the solution.

분석 메모

Control
Fetal human brain

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable