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Merck
모든 사진(1)

주요 문서

AB1255

Sigma-Aldrich

Anti-Cytochrome P450 Enzyme CYP1A1 and CYP1A2 Antibody

serum, Chemicon®

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

serum

항체 생산 유형

primary antibodies

클론

polyclonal

종 반응성

rat

제조업체/상표

Chemicon®

기술

ELISA: suitable
western blot: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... AHRR(57491)

특이성

Reacts with rat cytochrome P450 enzyme CYP1A1 and CYP1A2 on Western blots of hepatic microsomal fractions. No cross-reactivity with other cytochrome P450 enzymes.

면역원

Synthetic peptide

애플리케이션

Detect Cytochrome P450 Enzyme CYP1A1 & CYP1A2 using this Anti-Cytochrome P450 Enzyme CYP1A1 & CYP1A2 Antibody validated for use in ELISA & WB.
Research Category
Metabolism
Research Sub Category
Enzymes & Biochemistry
Western blot: useful for the simultaneous detection of rat CYP1A1 (57 kDa) and CYP1A2 (54 kDa), which can be separated electrophoretically.

Optimal working dilutions must be determined by end user.

물리적 형태

Rabbit antiserum. Liquid. Contains no preservative.

저장 및 안정성

Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

분석 메모

Control
POSITIVE CONTROL: rat hepatic microsomal fraction.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Identification of the epitope of an anti-peptide antibody which binds to CYP1A2 in many species including man
Edwards, R J, et al
Biochemical Pharmacology, 46, 213-220 (1993)
Synthetic peptide antigens elicit monoclonal and polyclonal antibodies to cytochrome P450 IA2.
Myers, M J, et al.
Biochemical and biophysical research communications, 169, 171-176 (1990)
Stephanie E Martinez et al.
Drug metabolism and disposition: the biological fate of chemicals, 47(11), 1314-1324 (2019-08-21)
Dogs are commonly used in human and veterinary pharmaceutical development. Physiologically based pharmacokinetic modeling using recombinant cytochrome P450 (CYP) enzymes requires accurate estimates of CYP abundance, particularly in liver. However, such estimates are currently available for only seven CYPs, which
A role of Wnt/beta-catenin signals in hepatic fate specification of human umbilical cord blood-derived mesenchymal stem cells.
Yoshida, Y; Shimomura, T; Sakabe, T; Ishii, K; Gonda, K; Matsuoka, S; Watanabe, Y; Takubo et al.
American Journal of Physiology: Gastrointestinal and Liver Physiology null

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