8.18586

Isophorone diisocyanate

(mixture of cis- and trans-isomers) for synthesis

• 동의어(들): Isophorone diisocyanate, 5-Isocyanato-1-isocyanatomethyl-1,3,3-trimethylcyclohexane, 3-Isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate
• 실험식(Hill 표기법): C₁₂H₁₈N₂O₂
• CAS Number: 4098-71-9
• Molecular Weight: 222.28
• MDL number: MFCD00064956
• UNSPSC 코드: 12352118
• EC 인덱스 번호: 223-861-6
• NACRES: NA.22

속성

• vapor pressure: 0.0004 hPa ( 20 °C)
• Quality Level: 200
• 분석: ≥99.0% (GC)
• 양식: liquid
• autoignition temp.: 430 °C
• 효능: 4825 mg/kg LD₅₀, oral (Rat); >7000 mg/kg LD₅₀, skin (Rat)
• expl. lim.: 0.7-4.5 % (v/v)
• bp: 158-159 °C/13 hPa
• mp: -60 °C
• 전이 온도: flash point 155 °C
• solubility: 0.015 g/L (slow decomposition)
• density: 1.06 g/cm³ at 20 °C
• 저장 온도: 2-30°C
• InChI: 1S/C12H18N2O2/c1-11(2)4-10(14-9-16)5-12(3,6-11)7-13-8-15/h10H,4-7H2,1-3H3
• InChI key: NIMLQBUJDJZYEJ-UHFFFAOYSA-N

설명

애플리케이션

• Thermoresponsive Random Poly(ether urethanes) with Tailorable LCSTs for Anticancer Drug Delivery.: This study explores the development of thermoresponsive random poly(ether urethanes) synthesized using Isophorone diisocyanate. These polymers exhibit adjustable lower critical solution temperatures (LCSTs), making them suitable for controlled anticancer drug delivery applications. The research highlights the potential of Isophorone diisocyanate in creating advanced materials for medical use, specifically in drug delivery systems (Sardon et al., 2015).

분석 메모

Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 1.060 - 1.062
Identity (IR): passes test

안전성 정보

• 픽토그램: GHS06,GHS08,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H315 - H317 - H319 - H330 - H334 - H335 - H411
• 예방조치 성명서: P260 - P273 - P280 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 1 Inhalation - Aquatic Chronic 2 - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 2
• Flash Point (°F): 325.4 °F - closed cup
• Flash Point (°C): 163 °C - closed cup