676493

VEGF Inhibitor, Flt₂₋₁₁

The VEGF Inhibitor, Flt2-11 controls the biological activity of VEGF. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

• 동의어(들): VEGF Inhibitor, Flt₂₋₁₁, NITVTLKKFPL, VEGFR Tyrosine Kinase Inhibitor X, VEGFR1 Kinase Inhibitor I
• 실험식(Hill 표기법): C₆₁H₁₀₄N₁₄O₁₅
• Molecular Weight: 1273.56
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 양식: lyophilized solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; desiccated (hygroscopic)
• 색상: white
• solubility: acetonitrile: 20%; DMSO: 5 mg/mL
• 배송 상태: ambient
• 저장 온도: 2-8°C

설명

일반 설명

An 11-amino acid peptide derived from the second Ig-like domain of vascular endothelial growth factor receptor-1 (VEGFR-1 or Flt-1) that is reported to inhibit angiogenesis in chick chorioallantoic membrane and VEGF-induced vascular permeability. Does not bind to vascular endothelial growth factor (VEGF) nor inhibit its binding to VEGFR. Reported to form a stable β-sheet structure and exists as a dimer in solution.

An 11-amino acid peptide derived from the second Ig-like domain of vascular endothelial growth factor receptor-1 (VEGFR-1 or Flt-1) that is shown to inhibit angiogenesis in chick chorioallantoic membrane and inhibits VEGF-induced vascular permeability. Neither binds to vascular endothelial growth factor (VEGF) nor inhibits its binding to VEGFR. Reported to form a stable β-sheet structure and exists as a dimer in solution.

생화학적/생리학적 작용

Cell permeable: no

Primary Target
VEGF

Product does not compete with ATP.

Reversible: no

포장

Packaged under inert gas

경고

Toxicity: Standard Handling (A)

서열

H-Asn-Ile-Thr-Val-Thr-Leu-Lys-Lys-Phe-Pro-Leu-OH

기타 정보

Tan, D.C., et al. 2001. FEBS Lett.494, 150.

법적 정보

Sold under license of U.S. Patent 6,200,954.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable