572631

SU5402

InSolution, ≥95%, Inhibits the tyrosine kinase activity of FGFR1

• 동의어(들): InSolution SU5402
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 양식: liquid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; desiccated (hygroscopic); protect from light
• 저장 온도: −70°C

설명

일반 설명

Inhibits the tyrosine kinase activity of FGFR1 (IC₅₀ = 10-20 µM in the presence of 1 mM ATP) by interacting with the catalytic domain of FGFR1. Also inhibits aFGF-induced phosphorylation of ERK1 and ERK2 (IC₅₀ = 10-20 µM). In contrast to SU4984, it acts only as a weak inhibitor of tyrosine phosphorylation of the PDGF receptor. Does not inhibit the phosphorylation of insulin receptor and exhibits no inhibitory effect on EGF receptor kinase.

포장

Packaged under inert gas

경고

Toxicity: Irritant (B)

물리적 형태

A 10 mM (500 µg/169 µl) solution of SU5402 (Cat. No. 572630) in DMSO.

재구성

Following initial thaw, aliquot and freeze (-70°C).

기타 정보

Mohammadi, M., et al. 1997. Science 276, 955.

법적 정보

Not available for sale in the United States.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): 188.6 °F - (refers to pure substance)
• Flash Point (°C): 87 °C - (refers to pure substance)