567570

Spectinomycin, Dihydrochloride, Pentahydrate, Streptomyces sp.

A broad spectrum aminoglycoside antibiotic that contains two glucose moieties. Footprint studies indicate that spectinomycin exerts regional effects on ribosomal structure.

• 동의어(들): Spectinomycin, Dihydrochloride, Pentahydrate, Streptomyces sp.
• 실험식(Hill 표기법): C₁₄H₂₄N₂O₇ · 2HCl · 5H₂O
• CAS Number: 22189-32-8
• Molecular Weight: 495.35
• MDL number: MFCD00150886
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 양식: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 색상: white to off-white
• solubility: water: 50 mg/mL
• 배송 상태: ambient
• 저장 온도: 2-8°C
• SMILES string: [Cl-].[Cl-].[N+H2]([C@@H]1[C@H]2O[C@@]3([C@H](O[C@@H]2[C@H]([C@@H]([C@@H]1O)[N+H2]C)O)O[C@@H](CC3=O)C)O)C.O.O.O.O.O
• InChI: 1S/C14H24N2O7.2ClH.5H2O/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14;;;;;;;/h5,7-13,15-16,18-20H,4H2,1-3H3;2*1H;5*1H2/t5-,7-,8+,9+,10+,11-,12-,13+,14+;;;;;;;/m1......./s1
• InChI key: DCHJOVNPPSBWHK-UXXUFHFZSA-N

설명

일반 설명

A broad spectrum aminoglycoside antibiotic that contains two glucose moieties. Footprint studies indicate that spectinomycin exerts regional effects on ribosomal structure. A resistance gene (aph) which encodes a spectinomycin has been cloned from Legionella pneumophila (disease agent for Legionnaire’s disease) kinase and expressed in E. coli. Potency: ≥500 µg/mg.

A broad spectrum aminoglycoside antibiotic that contains two glucose moieties. Footprint studies indicate that spectinomycin exerts regional effects on ribosomal structure. A resistance gene (aph) which encodes a spectinomycin has been cloned from Legionella pneumophila (disease agent for Legionnaire′s disease) kinase and expressed in E. coli.

생화학적/생리학적 작용

Primary Target
Footprint studies indicate that spectinomycin exerts regional effects on ribosomal structure

경고

Toxicity: Standard Handling (A)

기타 정보

Thompson, P.R., et al. 1998. J. Biol. Chem. 273, 14788.
Noah, J., and Wollenzien, P. 1997. Nucleic Acids Symp. Ser. 36, 178.
Suter, T.M., et al. 1997. Antimicrob. Agents Chemother. 41, 1385.
Thom, G., and Prescott, C.D. 1997. Bioorg. Med. Chem. 5, 1081.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable