567051-M

Sinefungin

InSolution, ≥95%, antibiotic

• 동의어(들): InSolution Sinefungin, SF, Adenosyl-ornithine, A9145
• 실험식(Hill 표기법): C₁₅H₂₃N₇O₅
• CAS Number: 58944-73-3
• Molecular Weight: 381.39
• MDL number: MFCD00865623
• UNSPSC 코드: 12352200

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 양식: liquid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; protect from light
• 저장 온도: −20°C
• SMILES string: [n]2(c3ncnc(c3nc2)N)[C@@H]1O[C@@H]([C@H]([C@H]1O)O)C[C@@H](N)CC[C@H](N)C(=O)O
• InChI: 1S/C15H23N7O5/c16-6(1-2-7(17)15(25)26)3-8-10(23)11(24)14(27-8)22-5-21-9-12(18)19-4-20-13(9)22/h4-8,10-11,14,23-24H,1-3,16-17H2,(H,25,26)(H2,18,19,20)/t6-,7-,8+,10+,11+,14+/m0/s1
• InChI key: LMXOHSDXUQEUSF-YECHIGJVSA-N

설명

일반 설명

An anti-leishmanial nucleoside antibiotic that acts as an S-adenosyl-L-methionine (SAM, AdoMet) methyltransferase-specific inhibitor.

생화학적/생리학적 작용

Primary Target
S-adenosyl-L-methionine (SAM, AdoMet) methyltransferase

경고

Toxicity: Standard Handling (A)

물리적 형태

A 10 mM (2 mg/524 µl) solution in H₂O.

재구성

Following initial thaw, aliquot and freeze (-20°C).

기타 정보

Cheng, D., et al. 2004. J. Biol. Chem.279, 23892.
Lin, Q., et al. 2001. J. Am. Chem. Soc.123, 11608.
Zingg, J.M., et al. 1996. Nucleic Acids Res.24, 3267.
McCammon, M.T., and Parks, L.W. 1981. J. Bacteriol.145, 106.
Pugh, C.S.G., et al. 1978. J. Biol. Chem.253, 4075.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3