561300

E-Selectin, Human, Recombinant, CHO Cells

• 동의어(들): CD62E, ELAM-1
• UNSPSC 코드: 12352202

속성

• 분석: ≥95% (SDS-PAGE)
• Quality Level: 100
• 형태: lyophilized
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 불순물: <1 EU/μg Endotoxin (EU/μg of E-Selectin)
• 배송 상태: wet ice
• 저장 온도: −20°C

설명

일반 설명

Recombinant, human E-selectin consisting of 535 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is transiently expressed on vascular endothelial cell surfaces where it is able to bind to ligands such as SLe^x found on leukocytes. This initial binding event is followed by a second interaction involving ICAM and VCAM-1 that leads to vascular penetration and leukocyte invasion into the extracellular matrix tissue.

Recombinant, human E-selectin consisting of 535 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is transiently expressed on vascular endothelial cell surfaces where it is able to bind to ligands, such as sialyl Lewis x found on leukocytes. This initial binding event is followed by a second interaction involving ICAM and VCAM-1 that leads to vascular penetration and leukocyte invasion into the extracellular matrix tissue.

생화학적/생리학적 작용

Shown to bind to E-selectin ligands on U937 cells.

경고

Toxicity: Standard Handling (A)

물리적 형태

Lyophilized from Dulbecco′s PBS with stabilizer.

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Reconstitute to 1 mg/ml with sterile H₂O.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1