539522

PKC_ε Translocation Inhibitor Peptide

The PKC_ε Translocation Inhibitor Peptide, Negative Control controls the biological activity of PKC_ε. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

• 동의어(들): PKC_ε Translocation Inhibitor Peptide, Protein Kinase Cε Translocation Inhibitor I, EAVSLKPT, PKCε Translocation Inhibitor I, PKCε-RACK2 Interaction Inhibitor I
• 실험식(Hill 표기법): C₃₇H₆₅N₉O₁₃
• Molecular Weight: 843.96
• UNSPSC 코드: 12352202
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥97% (HPLC)
• 형태: lyophilized solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; desiccated (hygroscopic)
• 색상: white
• solubility: water: 3 mg/mL
• 배송 상태: ambient
• 저장 온도: 2-8°C

설명

일반 설명

An octapeptide that selectively inhibits the translocation of PKC_ε to subcellular sites. Inhibition of PKC_ε translocation is known to specifically block phorbol ester or norepinephrine-mediated regulation of contraction in cardiomyocytes.

An octapeptide that selectively inhibits the translocation of protein kinase C_ε to subcellular sites in a reversible manner. Inhibition of PKC_ε translocation is known to specifically block phorbol ester- or norepinephrine-mediated regulation of contraction in cardiomyocytes.

생화학적/생리학적 작용

Cell permeable: no

Primary Target
PKCε Translocation

Product does not compete with ATP.

Reversible: yes

경고

Toxicity: Standard Handling (A)

서열

H-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH

물리적 형태

Supplied as a trifluoroacetate salt.

재구성

Following reconstitution, aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 6 months at -20°C.

기타 정보

Yedovitzky, M., et al. 1997. J. Biol. Chem. 272, 1417.
Johnson, J.A., et al. 1996. J. Biol. Chem.271, 24962.

법적 정보

Sold under license of U.S. Patent 5,783,405.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable