520219

PPACK II trifluoroacetate salt

≥95% (HPLC), solid, kallikrein inhibitor, Calbiochem^®

• 동의어(들): PPACK II, Trifluoroacetate Salt
• 실험식(Hill 표기법): C₂₅H₃₃ClN₆O₃ · 2C₂HF₃O₂
• CAS Number: 74392-49-7
• Molecular Weight: 729.07
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 제품명: PPACK II, Trifluoroacetate Salt, Potent and specific irreversible inhibitor of plasma and glandular kallikreins.
• Quality Level: 100
• 분석: ≥95% (HPLC)
• 양식: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; desiccated
• 색상: off-white
• solubility: water: 100 mg/mL
• 배송 상태: ambient
• 저장 온도: 2-8°C
• InChI: 1S/C25H33ClN6O3/c26-16-22(33)20(12-7-13-30-25(28)29)31-21(15-18-10-5-2-6-11-18)24(35)32-23(34)19(27)14-17-8-3-1-4-9-17/h1-6,8-11,19-21,31H,7,12-16,27H2,(H4,28,29,30)(H,32,34,35)/t19-,20+,21+/m1/s1
• InChI key: UFXAQJOOAQICNE-HKBOAZHASA-N

설명

일반 설명

Potent and specific irreversible inhibitor of plasma and glandular kallikreins. Also available as a 10 mM solution in H₂O (Cat. No. 508573).

Potent and specific irreversible inhibitor of plasma and glandular kallikreins. Inhibits the cleavage of atrial naturiuretic peptide (ANP 1-126) by kallikreins. Also inhibits adrenal kininogenase, a kallikrein-like enzyme.

생화학적/생리학적 작용

Cell permeable: no

Primary Target
Plasma and glandular kallikreins

Product does not compete with ATP.

Reversible: no

경고

Toxicity: Standard Handling (A)

서열

H-D-Phe-Phe-Arg-chloromethylketone, 2TFA

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

기타 정보

Byrne, R.E., and Scanu, A.M. 1989. J. Lipid Res. 30, 109.
Scicli, G., et al. 1989. Adv. Exp. Med. Biol.247B, 217.
Gibson, T.R., et al. 1987. Endocrinology120, 764.
Kettner, G., and Shaw, E. 1981. Methods Enzymol.80, 826.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable