콘텐츠로 건너뛰기
Merck
모든 사진(1)

주요 문서

511075

Sigma-Aldrich

Platelet Activating Factor-16

≥98% (TLC), lyophilized solid, inflammation mediator, Calbiochem®

동의어(들):

Platelet Activating Factor-16, PAF (C₁₆), 1-O-Palmityl-2-acetyl- sn-glycero-3-phosphocholine, 1-O-Hexadecyl-2-acetyl- sn-glycero-3-phosphocholine, PAF (C₁₆), 1-O-Palmityl-2-acetyl-sn-glycero-3-phosphocholine, 1-O-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine

로그인조직 및 계약 가격 보기


About This Item

실험식(Hill 표기법):
C26H54NO7P
CAS Number:
Molecular Weight:
523.68
MDL number:
UNSPSC 코드:
12352211
NACRES:
NA.77

제품명

Platelet Activating Factor-16, A potent mediator of inflammation that increases vascular permeability. Activates MAP kinases and MAP kinase kinase (MEK) in CHO cells.

Quality Level

분석

≥98% (TLC)

양식

lyophilized solid

제조업체/상표

Calbiochem®

저장 조건

OK to freeze
desiccated

색상

white to off-white

solubility

ethanol: 0.5-1 mg/mL
water: soluble

배송 상태

ambient

저장 온도

−20°C

SMILES string

[P](=O)([O-])(OC[C@H](OC(=O)C)COCCCCCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C26H54NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-31-23-26(34-25(2)28)24-33-35(29,30)32-22-20-27(3,4)5/h26H,6-24H2,1-5H3/t26-/m1/s1

InChI key

HVAUUPRFYPCOCA-AREMUKBSSA-N

일반 설명

Synthetic water-soluble platelet activating factor. A potent mediator of inflammation that increases vascular permeability. Activates MAP kinase and MAP kinase kinase (MEK) in CHO cells.
Synthetic. A potent mediator of inflammation that increases vascular permeability. Activates MAP kinases and MAP kinase kinase (MEK) in CHO cells.

생화학적/생리학적 작용

Cell permeable: no
Primary Target
MAP kinases and MAP kinase kinase (MEK)
Product does not compete with ATP.
Reversible: no

경고

Toxicity: Standard Handling (A)

재구성

Following reconstitution, aliquot and freeze (-20°C or -70°C) under an inert gas. Aqueous stock solutions are stable for up to 3 days at -20°C. Ethanol stock solutions are stable for up to 3 months at -70°C.

기타 정보

Honda, Z., et al. 1994. J. Biol. Chem. 269, 2307.
Mori, M., et al. 1994. Ann. N.Y. Acad. Sci.744, 107.
Pinckard, R.N., et al. 1992. J. Immunol.148, 3528.
Salari, H., et al. 1992. Biochem. Cell Biol.70, 129.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

R H Adamson et al.
American journal of physiology. Heart and circulatory physiology, 285(1), H406-H417 (2003-03-22)
We tested the hypothesis that acutely induced hyperpermeability is dependent on actin-myosin contractility by using individually perfused mesentery venules of pentobarbital-anesthetized rats. Venule hydraulic conductivity (Lp) was measured to monitor hyperpermeability response to the platelet-activating factor (PAF) 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine or bradykinin.

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.