444235-M

MMP-13 Substrate, Fluorogenic

A quenched fluorescence substrate for MMP-13 (collagenase-3; k_cat/Km = 1.09 x 10⁶ M⁻¹s⁻¹).

• 동의어(들): MMP-13 Substrate, Fluorogenic, Collagenase-3 Substrate, Fluorogenic
• 실험식(Hill 표기법): C₅₁H₆₅N₁₃O₁₅
• Molecular Weight: 1100.14
• UNSPSC 코드: 12352200

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: lyophilized solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; desiccated; protect from light
• 색상: yellow
• solubility: DMSO: 5 mg/mL
• 형광: λ_ex ~325 nm; λ_em ~393 nm
• 저장 온도: −20°C

설명

일반 설명

A quenched fluorescence substrate for MMP-13 (collagenase-3; k_cat/K_m = 1.09 x 10⁶ M^-1s^-1; excitation maximum: ~325 nm; emission maximum: ~393 nm). Less efficient as a substrate for MMP-1 (fibroblast collagenase) or MMP-8 (neutrophil collagenase).

생화학적/생리학적 작용

Primary Target
A quenched fluorescence substrate for MMP-13 (collagenase-3)

kcat/Km = 1.09 x 106 M⁻¹ sec⁻¹ for MMP-13 (collagenase-3)

경고

Toxicity: Standard Handling (A)

서열

MCA-Pro-Cha-Gly-Nva-His-Ala-Dpa-NH₂ [Cha = L-cyclohexylalanine; Dpa = 3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl; Nva = L-norvaline]

물리적 형태

Supplied as a trifluoroacetate salt.

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

기타 정보

Knauper, V., et al. 1996. J. Biol. Chem. 271, 1544.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable