441251

α₂-Macroglobulin, Human Plasma

A multifunctional, secreted glycoprotein that acts as a broad range irreversible protease inhibitor that forms a "trap" around most proteases.

• 동의어(들): α₂M, α₂MG
• UNSPSC 코드: 12352202
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥95% (SDS-PAGE)
• 형태: lyophilized
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• solubility: aqueous buffer: soluble
• 배송 상태: ambient
• 저장 온도: −20°C

설명

일반 설명

A multifunctional, secreted glycoprotein that acts as a broad range irreversible protease inhibitor that forms a "trap" around most proteases. α₂M is so large a molecule that it tends to remain intravascular. Localized on the surface of peripheral blood lymphocytes. Multifunctional activities include promoting growth of mammalian cells in culture, stimulating regeneration of lymphocytes in irradiated mice, transporting zinc, and acting as proteinase inhibitor that controls the clotting and fibrinolytic system.

생화학적/생리학적 작용

Cell permeable: no

Primary Target
broad range protease

Product does not compete with ATP.

Reversible: no

경고

Toxicity: Standard Handling (A)

물리적 형태

Lyophilized from 30 mM sodium phosphate buffer, with glycine, pH 7.0.

기타 정보

Bonner, J.C., et al. 1995. J. Biol. Chem. 270, 16236.
Lysiak, J.J., et al. 1995. J. Biol. Chem.270, 21919.
Boisset, N., et al. 1992. J. Struct. Biol.108, 221.
Barrett, A.J. 1980. Methods Enzymol.80, 737.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable