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Merck
모든 사진(1)

주요 문서

428017

Sigma-Aldrich

Anti-Lamp1 Mouse mAb (LY1C6)

liquid, clone LY1C6, Calbiochem®

동의어(들):

Anti-Lysosome-Associated Membrane Protein 1

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

항체 형태

purified antibody

항체 생산 유형

primary antibodies

클론

LY1C6, monoclonal

형태

liquid

포함

≤0.09% sodium azide as preservative

종 반응성

rat

제조업체/상표

Calbiochem®

저장 조건

OK to freeze
avoid repeated freeze/thaw cycles

동형

IgG1

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

일반 설명

Protein G purified mouse monoclonal antibody. Recognizes the ~120 kDa Lamp1 protein.
Recognizes the ~120 kDa Lamp1 protein.
This Anti-Lamp1 Mouse mAb (LY1C6) is validated for use in Immunoblotting, Immunocytochemistry, Immunofluorescence, Immunoprecipitation for the detection of Lamp1.

면역원

Rat
rat liver lysosomal membranes

애플리케이션

Immunoblotting (1 µg/ml, chemiluminescence)

Immunocytochemistry (1:100)

Immunofluorescence (see comments)

Immunoprecipitation (see comments)

포장

Please refer to vial label for lot-specific concentration.

경고

Toxicity: Standard Handling (A)

물리적 형태

In PBS containing 50% glycerol, pH 7.2.

재구성

Following initial thaw, aliquot and freeze (-20°C).

분석 메모

Positive Control
CHO-K1 cells

기타 정보

Kannan, K. et al. 1996. Cell Immunol.171, 10.
Rohrer, J., et al. 1996. J. Cell Biol. 132, 565.
Howe et al. 1988. PNAS85, 7577.
Lewis et al. 1985. J. Cell Biol.100, 1839.
This antibody has also been reported to work for immunofluorescence and immunoprecipitation. Antibody should be titrated for optimal results in individual systems.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Arvind Chhabra et al.
European journal of immunology, 34(10), 2824-2833 (2004-09-16)
Dendritic cells (DC) capture antigens from apoptotic and/or necrotic tumor cells and cross-present them to T cells, and various ways of delivering tumor antigens to DC in vitro and in vivo are being pursued. Since fusions of antigenic proteins with
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The American journal of pathology, 175(5), 1962-1974 (2009-10-10)
The multiplicity of cell death mechanisms induced by neonatal hypoxia-ischemia makes neuroprotective treatment against neonatal asphyxia more difficult to achieve. Whereas the roles of apoptosis and necrosis in such conditions have been studied intensively, the implication of autophagic cell death
Raymond E Hulse et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 28(47), 12199-12211 (2008-11-21)
In brain, monomeric immunoglobin G (IgG) is regarded as quiescent and only poised to initiate potentially injurious inflammatory reactions via immune complex formation associated with phagocytosis and tumor necrosis factor alpha (TNF-alpha) production in response to disease. Using rat hippocampal
Julien Puyal et al.
Annals of neurology, 66(3), 378-389 (2009-06-25)
To evaluate the contributions of autophagic, necrotic, and apoptotic cell death mechanisms after neonatal cerebral ischemia and hence define the most appropriate neuroprotective approach for postischemic therapy. Rats were exposed to transient focal cerebral ischemia on postnatal day 12. Some
Vanessa Ginet et al.
Autophagy, 10(5), 846-860 (2014-03-29)
Neuronal autophagy is increased in numerous excitotoxic conditions including neonatal cerebral hypoxia-ischemia (HI). However, the role of this HI-induced autophagy remains unclear. To clarify this role we established an in vitro model of excitotoxicity combining kainate treatment (Ka, 30 µM)

문서

Autophagy is a highly regulated process that is involved in cell growth, development, and death. In autophagy cells destroy their own cytoplasmic components in a very systematic manner and recycle them.

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