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Merck
모든 사진(1)

주요 문서

MABC39

Sigma-Aldrich

Anti-LAMP-1 (CD107a) Antibody, clone 1D4B

clone 1D4B, from rat

동의어(들):

lysosomal-associated membrane protein 1, lysosome-associated membrane glycoprotein 1, Lysosome-associated membrane protein 1, CD107 antigen-like family member A, CD107a antigen

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rat

Quality Level

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

1D4B, monoclonal

종 반응성

mouse

기술

flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

동형

IgG2aκ

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

mouse ... Lamp1(16783)

일반 설명

Lysosome-associated membrane protein 1 (LAMP-1) is a highly glycosolated, single-pass type 1 membrane protein belonging to the lysosome- associated membrane protein family; a group of proteins that make up the majority of the lysosomal membrane and are considered crucial mediators for cellular adhesion by interacting with carbohydrate receptors. LAMP-1 functions to traffic carbohydrate ligands to selectins. It is also thought to play a role in tumor cell metastasis.

면역원

NIH/3T3 plasma membrane fraction of mouse LAMP-1.

애플리케이션

Detect LAMP-1 (CD107a) using this Anti-LAMP-1 (CD107a) Antibody, clone 1D4B validated for use in WB, IP, IC, IH, FC.
Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP (Chen, 1985).

Immunocytochemistry Analysis: A previous lot was used by an independent laboratory in IC (Chen, 1985).
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional

Tumor Markers

품질

Evaluated by Western Blot in NIH/3T3 cell lysate.

Western Blot Analysis: 1:50,000 dilution of this antibody detected LAMP-1 in 10 µg of NIH/3T3 cell lysate.

표적 설명

~ 100 kDa observed. The calculated molecular weight of this protein is 44 kDa The protein is heavily glycosolated and therefore its molecular weight is typically noted from 95-115 kDa

물리적 형태

Format: Purified
Protein G
Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
NIH/3T3 cell lysate

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Urmi Bandyopadhyay et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(30), 11055-11060 (2014-07-16)
Lipofuscin, or aging pigment, is accreted as red autofluorescence in the lysosomes of motor neuron cell bodies in the ventral horn of WT mice by 3 mo of age. Strikingly, in two presymptomatic ALS mouse strains transgenic for mutant human

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