361550

BIO

≥97% (HPLC), solid, GSK-3GSK-3α/β inhibitor, Calbiochem

• 동의어(들): GSK-3 Inhibitor IX, BIO, (2ʹ Z,3ʹ E)-6-Bromoindirubin-3ʹ-oxime, BIO, (2ʹZ,3ʹE)-6-Bromoindirubin-3ʹ-oxime
• 실험식(Hill 표기법): C₁₆H₁₀BrN₃O₂
• CAS Number: 667463-62-9
• Molecular Weight: 356.17
• MDL number: MFCD08705318
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 제품명: GSK-3 Inhibitor IX, BIO, CAS 667463-62-9, is a cell-permeable, highly potent, selective, reversible, and ATP-competitive inhibitor of GSK-3α/β (IC₅₀ = 5 nM). Maintains self-renewal in human & mouse embryonic stem cells.
• Quality Level: 100
• 분석: ≥97% (HPLC)
• 양식: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; protect from light
• 색상: purple
• solubility: DMSO: 5 mg/mL
• 배송 상태: wet ice
• 저장 온도: 2-8°C
• SMILES string: Brc1cc2c(cc1)\C(=C3\Nc4c(cccc4)C\3N=O)\C(=O)N2
• InChI: 1S/C16H10BrN3O2/c17-8-5-6-9-12(7-8)19-16(21)13(9)15-14(20-22)10-3-1-2-4-11(10)18-15/h1-7,14,18H,(H,19,21)/b15-13-
• InChI key: WFRDXNRAUPBBTO-SQFISAMPSA-N

설명

생화학적/생리학적 작용

Cell permeable: yes

Product competes with ATP.

Reversible: yes

포장

Packaged under inert gas

경고

Toxicity: Carcinogenic / Teratogenic (D)

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3