344906

FURA 2/AM in Solution

• 동의어(들): FURA 2/AM in Solution
• 실험식(Hill 표기법): C₄₄H₄₇N₃O₂₄
• CAS Number: 108964-32-5
• Molecular Weight: 1001.85
• MDL number: MFCD00036976
• UNSPSC 코드: 12171500
• NACRES: NA.47

속성

• 분석: ≥95% (HPLC)
• Quality Level: 100
• 양식: liquid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; protect from light
• 형광: λ_ex 335 nm (high); λ_ex 362 nm (low); λ_em 505 nm (high); λ_em 512 nm (low)
• 배송 상태: ambient
• 저장 온도: −20°C
• InChI: 1S/C44H47N3O24/c1-25-7-8-32(46(16-38(53)65-20-60-26(2)48)17-39(54)66-21-61-27(3)49)35(13-25)58-11-12-59-42-31-14-36(43-45-15-37(71-43)44(57)69-24-64-30(6)52)70-34(31)10-9-33(42)47(18-40(55)67-22-62-28(4)50)19-41(56)68-23-63-29(5)51/h7-10,13-15H,11-12,16-24H2,1-6H3
• InChI key: UTBYGIDPBQOHNT-UHFFFAOYSA-N

설명

일반 설명

Cell-permeable ester form of FURA 2 (Cat. No. 344900). The active dye is rapidly released in the cell by cytoplasmic esterases. Fluorescent calcium chelator (K_d = 224 nM) that offers 30X greater fluorescence intensity that QUIN 2 (Cat. No. 551826). This probe has been used as a probe in many cellular systems, including cardiac myocytes, vascular smooth muscle cells, and medullary collecting tubules. Spectral properties in the presence of low calcium concentrations (excitation max.: 362 nm, emission max.: 512 nm) differ from those during high calcium conditions (excitation max.: 335 nm, emission max.: 505 nm).

생화학적/생리학적 작용

Cell permeable: no

Product does not compete with ATP.

Reversible: no

포장

Packaged under inert gas

경고

Toxicity: Irritant (B)

물리적 형태

A 1 mM solution of FURA 2/AM (Cat. No. 344905) in anhydrous DMSO.

재구성

Following initial thaw, aliquot and freeze (-20°C). Store frozen under an inert atmosphere.

기타 정보

Davis, M.J., et al. 1992. Am. J. Physiol. 263, H1292.
Rao, G.H., et al. 1992. Biochem. Med. Metab. Biol.47, 226.
Schwartz, Y., et al. 1992. Endocrinology131, 772.
Ward, C.A., and Moffat, M.P. 1992. J. Mol. Cell. Cardiol.24, 937.
Janconi, M.E., et al. 1990. J. Cell Biol.110, 1555.
Tsien, R.Y. 1980. Biochemistry19, 2396.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): 188.6 °F - closed cup - (Dimethylsulfoxide)
• Flash Point (°C): 87 °C - closed cup - (Dimethylsulfoxide)