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Merck
모든 사진(1)

주요 문서

33-016

Sigma-Aldrich

PI 3-Kinase HTRF® Assay; 384 wells

The PI 3-Kinase HTRF Assay is a high-performance assay kit that provides a universal method for testing all Class I PI3-Kinases in a homogeneous format. This pack size has a screening capacity of 1 plate.

동의어(들):

Assay for PI 3-Kinase, HTRF Assay, PI 3-Kinase Assay

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About This Item

UNSPSC 코드:
12161503
eCl@ss:
32161000
NACRES:
NA.84

Quality Level

종 반응성

human, mouse

제조업체/상표

HTRF®
Upstate®

기술

activity assay: suitable (kinase)

NCBI 수납 번호

UniProt 수납 번호

검출 방법

fluorometric (HTRF)

배송 상태

dry ice

유전자 정보

human ... PIK3CA(5290)

애플리케이션

Used to detect/quantify: PI 3-Kinase

생화학적/생리학적 작용

Target Sub-Family: PI3K/PI4K

포장

Kit capacity: 384 wells

성분

4X Reaction Buffer

PIP2 (Substrate; 1mM stock)

Stop Reagent A

Stop Reagent B

DM A Detection Reagent

DM B Detection Reagent

DM C Detection Reagent

법적 정보

HTRF is a registered trademark of Cis Bio International
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 2


시험 성적서(COA)

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문서 라이브러리 방문

James M J Dickson et al.
Bioscience reports, 33(6) (2013-08-24)
NTT (N-terminal tags) on the catalytic (p110) sub-unit of PI 3-K (phosphoinositol 3-kinase) have previously been shown to increase cell signalling and oncogenic transformation. Here we test the impact of an NT (N-terminal) His-tag on in vitro lipid and protein
Stephen Jamieson et al.
The Biochemical journal, 438(1), 53-62 (2011-06-15)
Genetic alterations in PI3K (phosphoinositide 3-kinase) signalling are common in cancer and include deletions in PTEN (phosphatase and tensin homologue deleted on chromosome 10), amplifications of PIK3CA and mutations in two distinct regions of the PIK3CA gene. This suggests drugs
Christina M Buchanan et al.
PloS one, 8(8), e71337-e71337 (2013-08-13)
In addition to lipid kinase activity, the class-I PI 3-kinases also function as protein kinases targeting regulatory autophosphorylation sites and exogenous substrates. The latter include a recently identified regulatory phosphorylation of the GM-CSF/IL-3 βc receptor contributing to survival of acute
Qin Li et al.
Toxicology research, 8(3), 353-360 (2019-06-05)
Qingkailing injection (QKLI) is a kind of multi-component traditional Chinese medicine injection. It has been widely used in clinical practice, but in recent years, it has caused more and more adverse reactions, mainly manifested as pseudo-allergic symptoms. To explore the

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