264151

Caspase-3 Substrate VII, Fluorogenic

Fluorogenic caspase-3 substrate.

• 동의어(들): Caspase-3 Substrate VII, Fluorogenic, Ac-DEVD-AFC
• 실험식(Hill 표기법): C₃₀H₃₄F₃N₅O₁₃
• Molecular Weight: 729.61
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 양식: lyophilized solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; desiccated; protect from light
• 색상: white
• solubility: DMSO: 5 mg/mL
• 형광: λ_ex ~400 nm; λ_em ~505 nm
• 배송 상태: ambient
• 저장 온도: −20°C

설명

일반 설명

Fluorogenic caspase-3 substrate (excitation maximum: ~400 nm; emission maximum: ~505 nm). Also acts as a substrate for granzyme B-processed ICE-LAP3, caspase-6, caspase-7, caspase-8, and caspase-10.

Fluorogenic caspase-3 substrate. Also acts as a substrate for granzyme B-processed caspase-6, caspase-7, caspase-8, and caspase-10.

생화학적/생리학적 작용

Cell permeable: no

Primary Target
Fluorogenic caspase-3 substrate

Product does not compete with ATP.

Reversible: no

경고

Toxicity: Standard Handling (A)

서열

Ac-Asp-Glu-Val-Asp-AFC

재구성

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

기타 정보

Keramaris, E., et al. 2000. Mol. Cell Neurosci. 15, 368.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable