218728

Caspase-9 Inhibitor III

The Caspase-9 Inhibitor III, also referenced under CAS 403848-57-7, controls the biological activity of Caspase-9. This small molecule/inhibitor is primarily used for Cancer applications.

• 동의어(들): Caspase-9 Inhibitor III, Ac-LEHD-CMK
• 실험식(Hill 표기법): C₂₄H₃₅ClN₆O₉
• CAS Number: 403848-57-7
• Molecular Weight: 587.02
• UNSPSC 코드: 12352200
• NACRES: NA.54

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 형태: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; desiccated
• 색상: white
• solubility: water: 1 mg/mL; DMSO: 5 mg/mL
• 배송 상태: ambient
• 저장 온도: −20°C

설명

일반 설명

A potent and irreversible inhibitor of caspase-9 (ICE-LAP6, Mch6). Reported to reduce myocardial infarct size during reperfusion (~70 nM).

A potent, irreversible inhibitor of caspase-9. Reported to reduce myocardial infarct size during reperfusion (~70 nM).

생화학적/생리학적 작용

Cell permeable: yes

Primary Target
caspase-9

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 70 nM against caspase-9

경고

Toxicity: Standard Handling (A)

서열

Ac-Leu-Glu-His-Asp-CMK

기타 정보

Mocanu, M.M., et al. 2000. Br. J. Pharmacol.130, 197.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable