16-220

Anti-phospho-Ser/Thr-Pro MPM-2 Antibody, Cy5 conjugate

Upstate^®, from mouse

• 동의어(들): Anti-MPM-2 Cy5 Antibody, Cy5 Anti-MPM-2, Phospho-Ser/Thr-Pro Detection
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• 결합: CY5 conjugate
• application: ICC; IF; WB
• 클론: monoclonal
• 종 반응성: vertebrates
• citations: 7
• 기술: immunocytochemistry: suitable; immunofluorescence: suitable; western blot: suitable

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: CY5 conjugate
• 항체 형태: purified antibody
• 항체 생산 유형: primary antibodies
• 클론: monoclonal
• 종 반응성: vertebrates
• 제조업체/상표: Upstate^®
• 기술: immunocytochemistry: suitable; immunofluorescence: suitable; western blot: suitable
• 동형: IgG1
• 배송 상태: wet ice
• 타겟 번역 후 변형: phosphorylation (pSer/pThr)

설명

일반 설명

This antibody recognizes a variety of proteins that are phosphorylated during mitosis.

Progression of cells from interphase to mitosis involves alterations in cell structures and activities. The transition from G2 to M phase is induced by M phase-promoting factor, or MPF. In M phase, many proteins are phosphorylated directly by MPF or indirectly by kinases activated by MPF. These M-phase phosphoproteins (MPPs, or MPHOSPHs) permit disassembly of interphase structures and generation of M-phase enzymatic activities and structures. Also, known as Forkhead-related protein FKHL16 or Hepatocyte nuclear factor 3 forkhead homolog 11.

특이성

Recognizes a phosphorylated epitope (phospho-[Ser/Thr]Pro) found in phosphoproteins such as MAP2, HSP70, cdc25, and DNA topoisomerase IIα, most of which are phosphorylated at the onset of mitosis. The number of phosphoproteins recognized by MPM-2 varies from species to species and with the cell type.

면역원

Mitotic human HeLa cell lysate

애플리케이션

Anti-phospho-Ser/Thr-Pro Antibody, MPM-2, Cy5 conjugate is a Mouse Monoclonal Antibody for detection of phospho-Ser/Thr-Pro also known as Mitotic protein #2 & has been tested in IF, WB, ICC.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Cell Cycle, DNA Replication & Repair

품질

Routinely evaluated by immunoblot on colcemid-treated HeLa cell lysates.

물리적 형태

100μg Cy5-conjugated mouse IgG₁ in 200μl of PBS containing 1% BSA, 0.05% Tween^®-20, 0.05% sodium azide.

Protein G Purified

저장 및 안정성

1 year at 4°C from date of shipment

분석 메모

Control
Colcemid-treated HeLa cell lysates

법적 정보

TWEEN is a registered trademark of Croda International PLC

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable