14-700

NEK11 Protein, active, 10 µg

• UNSPSC 코드: 12352202
• eCl@ss: 32160405

속성

• 재조합: expressed in baculovirus infected Sf21 cells
• Quality Level: 100
• 설명: protein target NEK11
• 정제법: (Ni²⁺/NTA-agarose)
• 기술: activity assay: suitable
• UniProt 수납 번호: Q8NG66
• 유전자 정보: human ... NEK11(79858)

설명

일반 설명

FUNCTION: SwissProt: Q8NG66 # Possible role in S-phase checkpoint mechanism.
COFACTOR: Manganese or magnesium.
SIZE: 645 amino acids; 74162 Da
SUBCELLULAR LOCATION: Nucleus. Nucleus, nucleolus. Note=Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase. Accumulates in the nucleolus in G1/S- arrested cells.
TISSUE SPECIFICITY: Poorly expressed in cerebellum, trachea, lung, appendix, and uterus.
DEVELOPMENTAL STAGE: Predominantly expressed at S/G2/M phase.
PTM: Phosphorylated.
SIMILARITY: SwissProt: Q8NG66 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. NIMA subfamily. & Contains 1 protein kinase domain.

품질

routinely evaluated by phosphorylation of MBP (Catalog # 13-104)

물리적 특성

59.3kDa

저장 및 안정성

6 months at -70°C from date of shipment

분석 메모

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H317
• 예방조치 성명서: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Hazard Classifications: Skin Sens. 1
• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable