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Merck
모든 사진(1)

Key Documents

14-623-M

Sigma-Aldrich

HIPK2 Protein, active, 10 µg

Active, N-terminal His6-tagged, recombinant, human HIPK2, amino acids 165-564, for use in Kinase Assays.

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About This Item

UNSPSC 코드:
12352202
eCl@ss:
32160405
NACRES:
NA.32

생물학적 소스

human

Quality Level

100
300

재조합

expressed in baculovirus infected Sf21 cells

분자량

Mw 49.6 kDa

제조업체/상표

Upstate®

기술

activity assay: suitable (kinase)

NCBI 수납 번호

UniProt 수납 번호

유전자 정보

human ... HIPK2(28996)

일반 설명

N-terminal His6-tagged, recombinant, human HIPK2, amino acids 165-564
Product Source: baculovirus in Sf21 insect cells

애플리케이션

Research Category
Inflammation & Immunology

생화학적/생리학적 작용

Protein Target: HIPK2
Target Sub-Family: CMGC

품질

routinely evaluated by phosphorylation of 0.33mg/ml MBP (Catalog # 13-104)

물리적 형태

Ni2+/NTA-agarose

저장 및 안정성

6 months at -70°C

기타 정보

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Skin Sens. 1

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Jae J Song et al.
The Journal of biological chemistry, 278(47), 47245-47252 (2003-09-12)
Overexpression of JNK binding domain inhibited glucose deprivation-induced JNK1 activation, relocalization of Daxx from the nucleus to the cytoplasm, and apoptosis signal-regulating kinase 1 (ASK1) oligomerization in human prostate adenocarcinoma DU-145 cells. However, SB203580, a p38 inhibitor, did not prevent
Y H Kim et al.
The Journal of biological chemistry, 273(40), 25875-25879 (1998-09-25)
A novel family of cofactors that differentially interact with homeoproteins have been identified via a yeast two-hybrid screen. The proteins contain a conserved protein kinase domain that is separated from a domain that interacts with homeoproteins and hence are termed
Jeffrey A Ecsedy et al.
Molecular and cellular biology, 23(3), 950-960 (2003-01-17)
We describe an interaction between homeodomain-interacting protein kinase 1 (HIPK1) and Daxx, two transcriptional regulators important in transducing growth-regulatory signals. We demonstrate that HIPK1 is ubiquitously expressed in mice and humans and localizes predominantly to the nucleus. Daxx normally resides

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