추천 제품
Agency
Ph. Eur.
Quality Level
제품 라인
EMPROVE® ESSENTIAL
양식
powder
응용 분야
pharmaceutical
solid formulation
solubility enhancement
저장 온도
15-25°C
InChI
1S/C2H4O/c1-2-3/h2-3H,1H2
InChI key
IMROMDMJAWUWLK-UHFFFAOYSA-N
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일반 설명
With a lower degree of hydrolysis along the PVA chain, Parteck® MXP 3-82 Polyvinyl alcohol is especially beneficial in forming strong interactions with hydrophobic drug molecules – in the solid state and in solution. Due to this, Parteck® MXP 3-82 excipient has very high capabilities as a precipitation inhibitor and can maintain high levels of supersaturation for physiologically relevant timescales. As a result, Parteck® MXP 3-82 Polyvinyl alcohol can provide solubility enhancement for even the most challenging molecules.
애플리케이션
Parteck® MXP 3-82 is a PVA-based excipient that is used in Hot Melt Extrusion for Solubility Enhancement in oral solid dosage forms.
특징 및 장점
- Superior supersaturation performance via precipitation inhibition
- High thermostability up to 250°C, extending the potential application range
- Stable high drug loads and suitability with a broad range of APIs
- Flexible release kinetics
- Compatible with several downstream processing capabilities, like direct compression, continuous manufacturing, thin film extrusion and 3D printing
- Optimized powder properties for excellent performance in the HME process
- Suitable polymer properties for HME, spray drying and 3D printing processes
법적 정보
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany
관련 제품
또한 이 제품과 함께 일반적으로 구입
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point (°F)
No data available
Flash Point (°C)
No data available
시험 성적서(COA)
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