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Merck
모든 사진(1)

Key Documents

13-107

Sigma-Aldrich

Core Histones

Highly pure core histones proteins (H2A, H2B, H3 and H4) including H1 purified from chicken erythrocytes, suitable as a substrate for histone modification assays (HAT, HDAC, DNMT) and nucleosome assembly studies.

동의어(들):

Core Histone Proteins

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About This Item

UNSPSC 코드:
12352200
eCl@ss:
32160405
NACRES:
NA.32

생물학적 소스

chicken

제조업체/상표

Upstate®

기술

activity assay: suitable (histone acetyltransferase (HAT))

배송 상태

dry ice

일반 설명

Histones are a family of basic proteins that associate with DNA in the nucleus and help condense it into chromatin. Some histones function as spools for the thread-like DNA to wrap around forming a nucleosome. Each nucleosome is made of DNA wrapped around eight histone proteins that function like a spool and are called a histone octamer. Each histone octamer is composed of two copies each of the histone proteins H2A, H2B, H3, and H4. The chain of nucleosomes is then wrapped into a 30 nm spiral called a solenoid, where additional H1 histone proteins are associated with each nucleosome to maintain the chromosome structure.

애플리케이션

Core histones and histone H1, purified from chicken erythrocytes; suitable as a substrate for HAT assays; purity = 90%

품질

rountinely evaluated by immunoblot using Anti-Histone H3 (05-499) and Anti-Histone H4 (07-108)

물리적 형태

Lyophilized

저장 및 안정성

Lyophilized: 2 years at -20°C; Rehydrated: 6 months at -70°C

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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