1.08386

Tris(hydroxymethyl)aminomethane

(Trometamol), EMPROVE^® EXPERT, Ph. Eur., BP, ChP, JPC, USP

• 동의어(들): Tromethamine, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Trometamol
• Linear Formula: NH₂C(CH₂OH)₃
• CAS Number: 77-86-1
• Molecular Weight: 121.14
• Beilstein: 741883
• MDL number: MFCD00004679
• UNSPSC 코드: 12352104
• EC 인덱스 번호: 201-064-4

속성

• Agency: BP; ChP; JPC; Ph. Eur.; USP
• Quality Level: 500
• vapor pressure: 0.0267 hPa ( 20 °C)
• 제품 라인: EMPROVE^® EXPERT
• 형태: solid
• pH: 10.2-10.6 (20 °C, 6 g/L in H₂O)
• 유용한 pH 범위: 7-9
• pKa(25 °C): 8.1
• bp: 219-220 °C/10 mmHg (lit.); 219-220 °C/13.3 hPa
• mp: 167-172 °C (lit.)
• solubility: 678 g/L
• density: 1.35 g/cm³ at 23 °C
• 응용 분야: ophthalmics; pharmaceutical
• 저장 온도: no temp limit
• SMILES string: NC(CO)(CO)CO
• InChI: 1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
• InChI key: LENZDBCJOHFCAS-UHFFFAOYSA-N

설명

일반 설명

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

애플리케이션

Tris(hydroxymethyl)aminomethane (Trometamol) is a commonly used buffer component in biomolecule downstream chromatography steps as well as final liquid formulation.

법적 정보

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable