1.04967

Potassium cyanide

for analysis EMSURE^® ACS,ISO,Reag. Ph Eur

• 동의어(들): Potassium cyanide, Cyanogen potassium
• 실험식(Hill 표기법): CKN
• CAS Number: 151-50-8
• Molecular Weight: 65.12
• MDL number: MFCD00011397
• UNSPSC 코드: 12352302
• EC 인덱스 번호: 205-792-3
• NACRES: NA.21

속성

• Grade: ACS reagent
• Quality Level: 300
• Agency: reag. ISO; reag. Ph. Eur.
• 제품 라인: EMSURE^®
• 분석: ≥97% (silver nitrate titration)
• 양식: solid
• 효능: 7.49 mg/kg LD₅₀, oral (Rat); 14.29 mg/kg LD₅₀, skin (Rabbit)
• pH: 11-12 (20 °C, 20 g/L in H₂O)
• bp: 1625 °C/1013 hPa
• mp: 634 °C
• density: 1.55 g/cm³ at 20 °C
• 벌크 밀도: 750 kg/m³
• 음이온 미량물: chloride (Cl^-): ≤0.02%; phosphate (PO₄^3-): ≤0.005%; sulfate (SO₄^2-): ≤0.01%; sulfide (S^2-): ≤0.0005%; thiocyanate (SCN^-): ≤0.01%
• 양이온 미량물: Fe: ≤0.01%; Na: ≤0.5%; Pb: ≤0.0002%
• 저장 온도: no temp limit
• SMILES string: [K+].N#[C-]
• InChI: 1S/CN.K/c1-2;/q-1;+1
• InChI key: NNFCIKHAZHQZJG-UHFFFAOYSA-N

설명

애플리케이션

• Identification of Iminium Intermediates Generation in the Metabolism of Tepotinib Using LC-MS/MS: In Silico and Practical Approaches to Bioactivation Pathway Elucidation.: The research identifies iminium intermediates in the metabolism of tepotinib using liquid chromatography-mass spectrometry. Potassium cyanide is utilized to trap reactive intermediates, providing insights into drug metabolism pathways (Abdelhameed et al., 2020).


• Synthesis of stable-isotope-labeled N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide and N-(3-dimethylaminopropyl)-N′-ethylurea.: This paper describes the synthesis of stable-isotope-labeled compounds using potassium cyanide in the synthesis process to understand the chemical structure and reactivity of these labeled compounds (Cao et al., 2020).


• Carbon-13 synthesis and NMR spectroscopic geometric isomer evaluation to support the filing of teriflunomide.: The study involves the synthesis of carbon-13 labeled teriflunomide and its isomers, using potassium cyanide in the synthetic pathway. The NMR spectroscopic analysis helped in the evaluation of geometric isomers (Kurz et al., 2021).


• A hybrid lipid membrane coating "shape-locks" silver nanoparticles to prevent surface oxidation and silver ion dissolution.: This research develops a hybrid lipid membrane to stabilize silver nanoparticles, using potassium cyanide in the analytical phase to measure the prevention of silver ion dissolution and oxidation (Miesen et al., 2020).

결합

Replaces: PX1435; PX1435-5; PX1435-1; PX1435-20

분석 메모

Assay (argentometric): ≥ 97.0 %
Chloride (Cl): ≤ 0.02 %
Phosphate (PO₄): ≤ 0.005 %
Sulfate (SO₄): ≤ 0.01 %
Sulphide (S): ≤ 0.0005 %
Thiocyanate (SCN): ≤ 0.01 %
Fe (Iron): ≤ 0.01 %
Na (Sodium): ≤ 0.5 %
Pb (Lead): ≤ 0.0002 %
Corresponds to ACS,Reag. Ph Eur

법적 정보

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS06,GHS08,GHS05,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H290,H300 + H310 + H330,H372,H410
• 예방조치 성명서: P262 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P314
• Hazard Classifications: Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - Met. Corr. 1 - STOT RE 1
• 표적 기관: Thyroid
• 보충제 위험성: EUH032
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable