1.00399

N,N-Dimethylacetamide

for headspace gas chromatography SupraSolv^®

• 동의어(들): N,N-Dimethylacetamide, Acetic acid dimethylamide, Acetyldimethylamine, DMAC, DMA, DMA
• Linear Formula: CH₃CON(CH₃)₂
• CAS Number: 127-19-5
• Molecular Weight: 87.12
• MDL number: MFCD00008686
• UNSPSC 코드: 12352111
• EC 인덱스 번호: 204-826-4
• NACRES: NA.03

속성

• vapor pressure: 1.76 hPa ( 20 °C)
• Quality Level: 100
• 제품 라인: SupraSolv^®
• 분석: ≥99.8% (GC)
• 형태: liquid
• autoignition temp.: 400 °C
• 효능: 5830 mg/kg LD₅₀, oral (Rat)
• expl. lim.: 1.7-11.5 % (v/v)
• 기술: GC-HS: suitable
• pH: 4 (20 °C, 200 g/L in H₂O)
• bp: 165-166 °C/1013 hPa
• mp: -20 °C
• 전이 온도: flash point 64 °C
• solubility: soluble >1000 g/L
• density: 0.94 g/cm³ at 20 °C
• 저장 온도: 2-30°C
• InChI: 1S/C4H9NO/c1-4(6)5(2)3/h1-3H3
• InChI key: FXHOOIRPVKKKFG-UHFFFAOYSA-N

설명

일반 설명

SupraSolv^® high-purity solvents for headspace gas chromatography (HS-GC) are developed particularly for the analysis of residual solvents (RS) in drug substances, excipients and drug products according to ICH (International Council for Harmonizaton of Technical Requirements for Registration of Pharmaceuticals for Human Use) Guideline Q3C»Impurities: Guideline for Residual Solvents«, European Pharmacopeia (Ph. Eur. Chapter 2.4.24) and United States Pharmacopeia (USP Chapter 467).

애플리케이션

Suitable as a solvent for analysis of residual solvents of ICH classes 1, 2 and 3 according to Ph. Eur. and USP:

• Every residual solvent of class 1 acc. ICH ≤ 1 µg/g
• Every residual solvent of class 2 acc. ICH ≤ 10 µg/g
• Every residual solvent of class 3 acc. ICH ≤ 50 µg/g

특징 및 장점

• high application reliability due to the application test performed on every batch produced
• application-oriented quality due to specified concentrations of residual solvents as defined by ICH

기타 정보

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

법적 정보

SUPRASOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS07,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H312 + H332 - H319 - H360D
• 예방조치 성명서: P202 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Repr. 1B
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flash Point (°F): 147.2 °F - closed cup
• Flash Point (°C): 64 °C - closed cup