09-874

Anti-SAP30 (yeast) Antibody

from rabbit

• 동의어(들): Sin3 corepressor complex subunit SAP30, Sin3-associated polypeptide, 30 kDa, Sin3-associated polypeptide, 30kDa, Sin3A-associated protein, 30kDa, histone deacetylase complex subunit SAP30
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 300
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 종 반응성: Saccharomyces cerevisiae
• 기술: western blot: suitable
• NCBI 수납 번호: NM_003864.3
• UniProt 수납 번호: P38429
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: Saccharomyces cerevisiae ... Sap30(855305)

설명

일반 설명

SAP30 (Sin3A-associated protein) is a widely expressed nuclear protein that is functionally conserved between human and yeast. It is a component of the multiprotein histone deacetylase complex containing the transcriptional repressor Sin3, multiple histone deacetylases (HDAC1 and HDAC2), histone binding proteins (RbAp46 and RbAp48) and other polypeptides. SAP30 can recruit the deacetylase complex to promoter DNA in a Sin3 independent manner and is involved in the recruitment of the mSin3 complex to a specific subset of N-CoR corepressor complexes. The latter function suggests a role for SAP30 in N-CoR-mediated repression. Furthermore, SAP30 may be involved in imparting target specificity to the deacetylase complex.

특이성

Not tested in other species.

Recognizes yeast SAP30 at ~27 kDa.

면역원

Epitope: a.a. 141-157

Immunogen was a synthetic peptide corresponding to a.a. 141-157 of yeast SAP30, conjugated to KLH.

애플리케이션

Anti-SAP30 (yeast) Antibody is a Rabbit Polyclonal Antibody for detection of SAP30 (yeast) also known as Sin3 corepressor complex subunit SAP30 & has been validated in WB.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Histones

Chromatin Biology

품질

Western Blot Analysis:
1 μg/ml of this antibody detected SAP30 in a yeast extract.

표적 설명

~27 kDa

물리적 형태

Format: Purified

Protein A purified IgG in 0.1M Tris-Glycine (pH7.4) 150 mM NaCl with 0.05% NaN3.

저장 및 안정성

Stable for 1 year at 2-8°C from date of shipment.

분석 메모

Control
Yeast extract

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids