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Merck
모든 사진(1)

주요 문서

07-692

Sigma-Aldrich

Anti-Sar1 Antibody

Upstate®, from rabbit

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모든 사진(1)

About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702

생물학적 소스

rabbit

항체 형태

purified antibody

항체 생산 유형

primary antibodies

클론

polyclonal

종 반응성

monkey, mouse, rat, human

제조업체/상표

Upstate®

기술

western blot: suitable

동형

IgG

NCBI 수납 번호

NM_020150.3

UniProt 수납 번호

Q9NR31
Q9Y6B6

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... ROR1(4919)

특이성

Sar1

면역원

KLH-conjugated, synthetic peptide corresponding to amino acids 46-62 (CKDDRLGQHVPTLHPTSE) of human Sar1 (a and b isoforms), with an N-terminal cysteine added for conjugation purposes

애플리케이션

Detect Sar1 using this Anti-Sar1 Antibody validated for use in WB.
Research Category
Signaling
Research Sub Category
G-proteins

Kinases & Phosphatases

품질

routinely evaluated by immunoblot on RIPA lysates from 3T3/A31 cells

표적 설명

Mr 21kDa

물리적 형태

Format: Purified
Protein A purified

저장 및 안정성

stable 2 years at -20°C from date of shipment

분석 메모

Control
Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Bethan Jones et al.
Nature genetics, 34(1), 29-31 (2003-04-15)
Dietary fat is an important source of nutrition. Here we identify eight mutations in SARA2 that are associated with three severe disorders of fat malabsorption. The Sar1 family of proteins initiates the intracellular transport of proteins in COPII (coat protein)-coated
A structural view of the COPII vesicle coat.
Bickford, Lincoln C, et al.
Current Opinion in Structural Biology, 14, 147-153 (2004)
Xue-Hai Liang et al.
Nucleic acids research, 46(19), 10225-10245 (2018-09-22)
RNase H1-dependent, phosphorothioate-modified antisense oligonucleotides (PS-ASOs) can enter cells through endocytic pathways and need to be released from the membrane-enclosed organelles, a limiting step for antisense activity. Accumulating evidence has suggested that productive PS-ASO release mainly occurs from late endosomes
The intracellular transport of chylomicrons requires the small GTPase, Sar1b.
Shoulders, Carol C, et al.
Current Opinion in Lipidology, 15, 191-197 (2004)
François-Xavier Campbell-Valois et al.
Molecular & cellular proteomics : MCP, 11(7), M111-M111 (2012-03-20)
Phagosomes, by killing and degrading pathogens for antigen presentation, are organelles implicated in key aspects of innate and adaptive immunity. Although it has been well established that phagosomes consist of membranes from the plasma membrane, endosomes, and lysosomes, the notion
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