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Merck
모든 사진(1)

주요 문서

07-532

Sigma-Aldrich

Anti-phospho-PKR (Thr446) Antibody

Upstate®, from rabbit

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

polyclonal

종 반응성

human

제조업체/상표

Upstate®

기술

western blot: suitable

동형

IgG

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

타겟 번역 후 변형

phosphorylation (pThr446)

유전자 정보

human ... EIF2AK2(5610)

특이성

phospho-PKR

면역원

Peptide corresponding to amino acids surrounding Thr446 of human PKR.

애플리케이션

Anti-phospho-PKR (Thr446) Antibody is an antibody against phospho-PKR (Thr446) for use in WB.
Research Category
Signaling
Research Sub Category
Cytoskeletal Signaling

품질

routinely evaluated by immunoblot in RIPA lysates from HeLa cells that had been stimulated with IFN alpha overnight followed by treatment with calyculin A for 15 minutes

표적 설명

68 kDa

물리적 형태

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein A purified

저장 및 안정성

2 years at -20°C

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1


시험 성적서(COA)

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문서 라이브러리 방문

X Saelens et al.
The Journal of biological chemistry, 276(45), 41620-41628 (2001-09-14)
The protein kinase PKR is a major player in the cellular antiviral response, acting mainly by phosphorylation of the alpha-subunit of the eukaryotic translation initiation factor 2 (eIF2-alpha) to block de novo protein synthesis. PKR activation requires binding of double-stranded
Dario Paolo et al.
Plants (Basel, Switzerland), 10(2) (2021-01-28)
Seed size is the result of complex molecular networks controlling the development of the seed coat (of maternal origin) and the two fertilization products, the embryo and the endosperm. In this study we characterized the role of Arabidopsis thaliana MADS-domain
Ka-Chun Suen et al.
The Journal of biological chemistry, 278(50), 49819-49827 (2003-09-17)
One of the hallmarks of Alzheimer's disease is extracellular accumulation of senile plaques composed primarily of aggregated beta-amyloid (Abeta) peptide. Treatment of cultured neurons with Abeta peptide induces neuronal death in which apoptosis is suggested to be one of the
Shien Hu et al.
Gastroenterology, 133(6), 1893-1904 (2007-12-07)
Inducible heat shock proteins (iHsp), Hsp25/27 and Hsp70, play essential roles in protecting cells against stress and, in intestinal mucosal inflammation, potentially lessening the extent and severity of injury. We examined the expression and regulation of iHsp in human and
Shuen-Ing Tschen et al.
Diabetes, 58(6), 1312-1320 (2009-02-21)
The aim of this study was to elucidate whether age plays a role in the expansion or regeneration of beta-cell mass. We analyzed the capacity of beta-cell expansion in 1.5- and 8-month-old mice in response to a high-fat diet, after

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