추천 제품
생물학적 소스
rabbit
Quality Level
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
polyclonal
종 반응성
mouse, pig, guinea pig, rat, canine, human, bovine
제조업체/상표
Upstate®
기술
western blot: suitable
동형
IgG
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
타겟 번역 후 변형
unmodified
유전자 정보
bovine ... Nos3(287024)
dog ... Nos3(403784)
guinea pig ... Nos3(100135577)
human ... NOS3(4846)
mouse ... Nos3(18127)
pig ... Nos3(397557)
rat ... Nos3(24600)
일반 설명
Endothelial NOS (eNOS), also known as Nitric oxide synthase 3 (NOS3) or constitutive NOS (cNOS), is a nitric oxide synthase. It generates NO in blood vessels and is involved with regulating vascular function. A constitutive Ca2+ dependent NOS provides a basal release of NO. eNOS is associated with plasma membranes surrounding cells and the membranes of Golgi bodies within cells.
특이성
Predicted to cross-react with mouse, guinea pig, pig, rat and dog based on sequence homology.
Recognizes eNOS/NOS III, Mr ~135 kDa.
면역원
KLH-conjugated, synthetic peptide corresponding to amino acids 1181-1194 (C-QERQLRGAVPWAFD) of human eNOS/NOS III. The immunizing sequence has 10/11 identical amino acids in mouse, guinea pig, bovine, pig, rat, and dog.
애플리케이션
Anti-eNOS/NOS III Antibody, CT detects level of eNOS/NOS III & has been published & validated for use in WB.
품질
Routinely evaluated by western blot in RIPA lysates from HUVEC cells.
Western Blot Analysis:
0.5-2 µg/mL of this lot detected eNOS/NOS III in RIPA lysates from HUVEC cells.
Western Blot Analysis:
0.5-2 µg/mL of this lot detected eNOS/NOS III in RIPA lysates from HUVEC cells.
표적 설명
135 kDa
물리적 형태
Format: Purified
Purified rabbit polyclonal IgG in buffer containing 0.014 M phosphate buffer, pH 7.6, 0.175 M NaCl, 0.07% sodium azide before the addition of glycerol to 30%. Liquid at -20°C.
분석 메모
Control
Platelets, placenta, liver and kidney.
Platelets, placenta, liver and kidney.
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
법적 정보
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Apigenin inhibits the TNF?-induced expression of eNOS and MMP-9 via modulating Akt signalling through oestrogen receptor engagement.
Daniela Palmieri,Patrizia Perego,Domenico Palombo
Molecular and Cellular Biochemistry null
The senescence-accelerated mouse (SAM-P8) as a model for the study of vascular functional alterations during aging.
Llorens, Silvia, et al.
Biogerontology, 8, 663-672 (2007)
Fetal pulmonary vascular remodeling in a rat model induced by hypoxia and indomethacin.
Xue-Feng Xu,Wei-Zhong Gu,Xi-Ling Wu,Ru-Yi Li,Li-Zhong Du
The Journal of Maternal-Fetal & Neonatal Medicine : The Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians null
BDNF/TrkB content and interaction with gastrin-releasing peptide receptor blockade in colorectal cancer.
Caroline Brunetto de Farias,Denis Broock Rosemberg,Tiago Elias Heinen et al.
Oncology null
TJ0711, a novel vasodilatory ?-blocker, protects SHR rats against hypertension induced renal injury.
Yang, Juan, et al.
American Journal of Translational Research, 5, 279-290 (2013)
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