추천 제품
생물학적 소스
rabbit
Quality Level
결합
ALEXA FLUOR™ 488
항체 형태
purified antibody
항체 생산 유형
primary antibodies
클론
polyclonal
종 반응성
human
종 반응성(상동성에 의해 예측)
chicken (based on 100% sequence homology), rat (based on 100% sequence homology), mouse (based on 100% sequence homology)
농도
0.5 mg/mL
기술
immunocytochemistry: suitable
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
trimethylation (Lys9)
유전자 정보
human ... H3C1(8350)
mouse ... H3C1(360198)
rat ... H3C1(679994)
일반 설명
Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. Histone proteins are highly post-translationally modified, and Histone H3 is the most extensively modified of the five histones. Histone H3 sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Di- and tri-methylation of histone H3 are gene silencing marks, while removal of these marks by the demethylase genes Jmjd1a and Jmjd2c leads to gene activation. This product is a conjugated version of Cat. No. 07-442.
면역원
Linear peptide corresponding to Histone H3 trimethylated at Lys9.
애플리케이션
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
This Anti-trimethyl Histone H3 (Lys9) Antibody, Alexa Fluor™ 488 Conjugate is validated for use in ICC for the detection of trimethyl Histone H3 (Lys9).
품질
Evaluated by Immunocytochemistry in HeLa cell lysate.
Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected trimethyl Histone H3 (Lys9) in HeLa cells.
Alexa Fluor™ is a registered trademark of Life Technologies.
Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected trimethyl Histone H3 (Lys9) in HeLa cells.
Alexa Fluor™ is a registered trademark of Life Technologies.
표적 설명
~17 kDa observed (Refer to Cat. No. 07-442)
물리적 형태
Protein A purified
Purified rabbit conjugate in buffer containing PBS with 15 mg/ml BSA and 0.1% Sodium Azide.
저장 및 안정성
Stable for 1 year at 2-8°C from date of receipt.
법적 정보
ALEXA FLUOR is a trademark of Life Technologies
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Gayani Batugedara et al.
Microbial genomics, 6(2) (2020-02-06)
Proteins interacting with DNA are fundamental for mediating processes such as gene expression, DNA replication and maintenance of genome integrity. Accumulating evidence suggests that the chromatin of apicomplexan parasites, such as Plasmodium falciparum, is highly organized, and this structure provides
Maegan L Capitano et al.
The Journal of clinical investigation, 129(6), 2555-2570 (2019-05-21)
The nuclear protein DEK is an endogenous DNA-binding chromatin factor regulating hematopoiesis. DEK is one of only 2 known secreted nuclear chromatin factors, but whether and how extracellular DEK regulates hematopoiesis is not known. We demonstrated that extracellular DEK greatly
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