추천 제품
생물학적 소스
rabbit
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
정제법
affinity chromatography
종 반응성
human, mouse
기술
dot blot: suitable
western blot: suitable
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
유전자 정보
human ... H2AX(3014)
mouse ... H2Ax(15270)
rat ... H2Ax(500987)
일반 설명
Histone H2A is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H2A is involved with the structure of the nucleosomes of the ′beads on a string′ structure. The phosphorylated form of H2A.X is thought to be invloved with DNA repair, possibly through reorganizing chromatin into a more open state and allowing the recruitment of proteins to repair DNA double stranded breaks.
면역원
KLH-conjugated linear peptide corresponding to the C-terminus of human phospho Histone H2A.X phosphorylated at Tyr142.
애플리케이션
Anti-phospho Histone H2A.X Antibody (Tyr142) is a highly specific rabbit polyclonal antibody, that targets Histone H2A.X & has been tested in western blotting & Dot Blot.
Dot Blot Analysis: 0.5 µg/mL from a representative lot detected phospho Histone H2A.X (Tyr142) peptides, but not phospho Histone H2A.X (Tyr142) peptides or other peptides corresponding to modified histones.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Histones
Histones
품질
Evaluated by Western Blotting in colcemid treated HeLa cell lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected phospho Histone H2A.X (Tyr142) in colcemid treated HeLa cell lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected phospho Histone H2A.X (Tyr142) in colcemid treated HeLa cell lysate.
표적 설명
~16 kDa observed. Uncharacterized band(s) may be observed in some cell lysates.
물리적 형태
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
저장 및 안정성
Stable for 1 year at 2-8°C from date of receipt.
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
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