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Merck
모든 사진(1)

주요 문서

07-1407

Sigma-Aldrich

Anti-GLUT-8 Antibody, CT

from rabbit

동의어(들):

Glucose transporter type 8, Glucose transporter type X1, glucose transporter X1, solute carrier family 2 (facilitated glucose transporter)

member 8, solute carrier family 2 (facilitated glucose transporter),

member 8

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41
클론:
polyclonal
application:
IHC
종 반응성:
human
기술:
immunohistochemistry: suitable (paraffin)
citations:
2

생물학적 소스

rabbit

Quality Level

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

종 반응성

human

종 반응성(상동성에 의해 예측)

mouse

기술

immunohistochemistry: suitable (paraffin)

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... SLC2A8(29988)
mouse ... Slc2A8(56017)

일반 설명

GLUT-8 is a glucose transporter facilitated by the regulation of insulin, binding cytochalasin B such that the orientation is glucose-inhibitive. In appearance, the transporter seems to be a dual-specific sugar transporter since fructose can also be inhibitive. GLUT-8 is expressed largely in the testis, where down-regulation is facilitated by estrogen. However, GLUT-8 is not highly expressed in testicular carcinoma. Lower levels of GLUT-8 are present in most other tissues.

특이성

Recognizes GLUT-8.

면역원

An 11 amino acid sequence near the C-terminus of mouse Glut-8 (Doege et al. 2000; Carayannopoulos et al. 2000)
Epitope: C-terminus

애플리케이션

Anti-GLUT-8 Antibody, C-terminus detects level of GLUT-8 & has been published & validated for use in IH(P).
Research Category
Signaling
Research Sub Category
Insulin/Energy Signaling

품질

Evaluated by Immunohistochemistry in human kidney tissue
Immunohistochemistry Analysis: 1:100 dilution of this lot detected GLUT-8 in human kidney tissue.

표적 설명

Approx. 50 kDa

결합

Replaces: AB3140

물리적 형태

Format: Purified
ImmunoAffinity Purified
Liquid in PBS with 0.1% BSA.

저장 및 안정성

Maintain at -20°C in undiluted aliquots for up to 1 year from date of receipt. Avoid repeated freeze/thaw cycles.

분석 메모

Control
Human kidney tissue.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Jimena Laporta et al.
PloS one, 8(2), e57847-e57847 (2013-03-08)
The aim of this experiment was to demonstrate the ability of feeding serotonin (5-HT; 5-hydroxytryptamine) precursors to increase 5-HT production during the transition from pregnancy to lactation and the effects this has on maternal energy metabolism in the liver and

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

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