추천 제품
생물학적 소스
rabbit
Quality Level
항체 형태
affinity purified immunoglobulin
항체 생산 유형
primary antibodies
클론
polyclonal
정제법
affinity chromatography
종 반응성
human, mouse, rat
제조업체/상표
Upstate®
기술
western blot: suitable
동형
IgG
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
타겟 번역 후 변형
phosphorylation (pThr187)
유전자 정보
human ... CDKN1B(1027)
특이성
phosphorylated Kip1
면역원
KLH-conjugated, synthetic peptide (C-PNAGSVEQ[pT]PKK) corresponding to amino acids 179-190 of human Kip1
애플리케이션
Anti-phospho-Kip1 (Thr187) Antibody is a high quality Rabbit Polyclonal Antibody for the detection of phospho-Kip1 (Thr187) & has been validated in WB.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair
Cell Cycle, DNA Replication & Repair
품질
routinely evaluated by immunoblot on a HeLa cell RIPA lysate
표적 설명
27kDa
물리적 형태
0.2M Tris, 0.15 M NaCl, 0.1mM EDTA, 0.05% sodium azide before the addition of glycerol to 30%
Immunoaffinity Chromatography
저장 및 안정성
1 year at -20°C
법적 정보
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Shuichan Xu et al.
The Journal of biological chemistry, 282(21), 15462-15470 (2007-04-06)
p27, an important cell cycle regulator, blocks the G(1)/S transition in cells by binding and inhibiting Cdk2/cyclin A and Cdk2/cyclin E complexes (Cdk2/E). Ubiquitination and subsequent degradation play a critical role in regulating the levels of p27 during cell cycle
J Kato
Frontiers in bioscience : a journal and virtual library, 4, D787-D792 (1999-11-30)
The first gap phase (G1) in the mammalian cell cycle plays a pivotal role in determining whether or not cells are to initiate DNA replication. Progression through G1 phase and transition into S phase are positively and negatively regulated by
G Wolf
Kidney international, 56(4), 1262-1265 (1999-10-03)
There are two fundamentally different growth responses for cells comprising the nephron: hyperplasia or hypertrophy. Cells that progress through the normal cell cycle double their DNA content and eventually divide during mitosis. Those cells that hypertrophy stop the growth process
p27KIP1, an inhibitor of cyclin-dependent kinases.
Koff, A and Polyak, K
Progress in Cell Cycle Research, 1, 141-147 (1995)
Oncostatin M induces growth arrest by inhibition of Skp2, Cks1, and cyclin A expression and induced p21 expression.
Halfter, H; Friedrich, M; Resch, A; Kullmann, M; Stogbauer, F; Ringelstein, EB; Hengst, L
Cancer Research null
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