06-1385

Anti-PDX1 (goat) Antibody

serum, from goat

• 동의어(들): pancreatic and duodenal homeobox 1, pancreatic-duodenal homeobox factor 1, somatostatin transcription factor 1, insulin promoter factor 1, homeodomain transcription factor, Insulin promoter factor 1, Somatostatin-transactivating factor 1, Insulin upstrea
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: goat
• Quality Level: 100
• 항체 형태: serum
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 종 반응성: human, mouse
• 기술: immunohistochemistry: suitable; western blot: suitable
• NCBI 수납 번호: NP_032840
• UniProt 수납 번호: P52946
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: mouse ... Pdx1(18609)

설명

일반 설명

Transcription factor PDX1, also known as pancreatic and duodenal homeobox 1, activates expression of the insulin and somatostatin genes. This protein is a key regulator of islet peptide hormone expression and also plays an essential role in pancreatic development. It has been shown to interact with the basic helix-loop-helix domains of TCF3(E47) and NEUROD1 and with HMG-I(Y). This protein also interacts with the methyltransferase SETD7. Mutations in this gene may be involved in several disorders of the pancreas or in diabetes mellitus.

면역원

Recombinant protein corresponding to the N-terminus of mouse PDX1.

애플리케이션

Anti-PDX1 (goat) Antibody is a Goat Polyclonal Antibody for detection of PDX1 also known as pancreatic & duodenal homeobox 1, somatostatin transcription factor 1, Insulin promoter factor 1 & has been validated in WB & IHC.

Immunohistochemistry Analysis: 1:400 dilution from a represenative lot detected PDX1 in normal human pancreas tissue.

품질

Evaluated by Western Blot in mouse pancreatic β T-cell lysate.

Western Blot Analysis: 1:1,000 dilution of this antibody detected PDX1 on 10 µg of mouse pancreatic β T-cell lysate.

표적 설명

~ 39 kDa

물리적 형태

Unpurified goat polyclonal serum containing 0.05% sodium azide.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1