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BQ-788, Sodium Salt

• 동의어(들): BQ-788, Sodium Salt, N- cis-2,6-Dimethylpiperidinocarbonyl-L-γ-MeLeu-D-Trp(MeOCO)-D-Nle-OH, Na
• 실험식(Hill 표기법): C₃₄H₅₀N₅NaO₇
• Molecular Weight: 663.78
• UNSPSC 코드: 12352200
• NACRES: NA.28

속성

• 분석: ≥95% (HPLC)
• Quality Level: 100
• 형태: lyophilized solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; desiccated
• 색상: white to off-white
• solubility: 0.01% NH₄OH: 1 mg/mL; DMSO: 2 mg/mL; methanol: water (3:1): 2 mg/mL
• 배송 상태: ambient
• 저장 온도: −20°C

설명

일반 설명

A highly selective and competitive ETB receptor antagonist (IC₅₀ = 1.2 nM).

Highly selective ET_B-receptor antagonist (IC₅₀ = 1.2 nM).

생화학적/생리학적 작용

Cell permeable: no

Primary Target
ETB-receptor antagonist

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 1.2 nM as ETB-receptor antagonist

경고

Toxicity: Standard Handling (A)

재구성

Following reconstitution, aliquot and freeze (-20°C). DMSO and Methano:H₂O stock solutions are stable for up to 2 months at -20°C.

기타 정보

Okada, M., and Nishikibe, M. 2002. Cardiovasc. Drug Reviews20, 53.
Taniai, H., et al. 2001. Hepatology33, 894.
Fukuroda, T., et al. 1994. Biochem. Biophys. Res. Commun.199, 1461.
Ishikawa, K., et al. 1994. Proc. Natl. Acad. Sci. USA91, 4892.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable