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Merck
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Key Documents

04-901

Sigma-Aldrich

Anti-NR2A Antibody, clone A12W, rabbit monoclonal

culture supernatant, clone A12W, Upstate®

동의어(들):

Anti-EPND, Anti-FESD, Anti-GluN2A, Anti-LKS, Anti-NMDAR2A, Anti-NR2A

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

culture supernatant

항체 생산 유형

primary antibodies

클론

A12W, monoclonal

종 반응성

mouse, rat

제조업체/상표

Upstate®

기술

western blot: suitable

동형

IgG

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... GRIN2A(2903)

특이성

NR2A

면역원

6His-tagged fusion protein corresponding to amino acids 1265-1464 of mouse NMDA receptor 2A (NR2A)

애플리케이션

Anti-NR2A Antibody, clone A12W is an antibody against NR2A for use in WB.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

품질

routinely evaluated by immunoblot on rat brain microsomal preparations (Catalog#12-144)

표적 설명

Mr 170kDa

물리적 형태

Cultured supernantant in 0.05% sodium azide

저장 및 안정성

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1


시험 성적서(COA)

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Kalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and function.
Kiraly, DD; Lemtiri-Chlieh, F; Levine, ES; Mains, RE; Eipper, BA
The Journal of Neuroscience null
Marie Lise Frandemiche et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(17), 6084-6097 (2014-04-25)
Tau is a microtubule-associated protein well known for its stabilization of microtubules in axons. Recently, it has emerged that tau participates in synaptic function as part of the molecular pathway leading to amyloid-beta (Aβ)-driven synaptotoxicity in the context of Alzheimer's
Chihiro Nozaki et al.
Nature neuroscience, 14(8), 1017-1022 (2011-07-05)
Zinc is abundant in the central nervous system and regulates pain, but the underlying mechanisms are unknown. In vitro studies have shown that extracellular zinc modulates a plethora of signaling membrane proteins, including NMDA receptors containing the NR2A subunit, which
Melissa A Snyder et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 38(2), 328-340 (2012-09-13)
The N-methyl-D-aspartate (NMDA) receptor has long been associated with learning and memory processes as well as diseased states, particularly in schizophrenia (SZ). Additionally, SZ is increasingly recognized as a neurodevelopmental disorder with cognitive impairments often preceding the onset of psychosis.
Visualization of structural changes accompanying activation of N-methyl-D-aspartate (NMDA) receptors using fast-scan atomic force microscopy imaging.
Suzuki, Y; Goetze, TA; Stroebel, D; Balasuriya, D; Yoshimura, SH; Henderson, RM; Paoletti et al.
The Journal of Biological Chemistry null

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