추천 제품
종 반응성
human
Quality Level
제조업체/상표
SMC®
assay range
sensitivity: 0.23 pg/mL
(Lower Limit of Quantification)
inter-assay cv: ≤6%
intra-assay cv: ≤5%
(Intra-assay CV n=5; Inter-assay n=3)
일반 설명
Glial fibrillary acidic protein (GFAP) is a type III intermediate filament protein produced notably by astrocytes during CNS development, and functions in astrocyte regeneration, plasticity, and also contributes to function of the blood brain barrier. GFAP is a potential biomarker in a number of neurodegenerative diseases as well as in traumatic brain injury. There is much interest today in measuring GFAP levels in low abundance, because not only does it make it possible to evaluate this protein as a blood biomarker, but also enables researchers to study the downregulation of GFAP in therapeutic research. The new SMC® Human GFAP High Sensitivity Immunoassay Kit enables accurate measurement of this protein in human serum, plasma, and cerebrospinal fluid, harnessing the power of the SMCxPRO® ultrasensitive immunoassay system.
특이성
Non Human Primate – 100%
Mouse – 100%
Rat – 100%
Canine – 100%
Feline – 100%
Note: This assay was tested for cross-reactivity with Ventimin, NFL, UCHL1 and total Tau. No cross-reactivity was detected with any of these analytes.
애플리케이션
This new streamline kit has the following features:
- Improved options for sample prep and incubation
- Lyophilization protein standard for uniform shipping and storage condition
- Increased reagent volumes to accommodate automation
- Able to achieve assay specifications on both SMCxPRO® and Erenna.
Research Category:
Neuroscience
neurological
Research Sub-Category:
Alzheimer′s Disease
Aging, Nervous System
Neurodegenerative Diseases
Neurofilament & Neuron Metabolism
Neuronal & Glial Markers
Neuroregenerative Medicine
Neuroscience
성분
- Assay Buffer
- GFAP Coated Beads
- Standard Diluent
- GFAP Detection Antibody
- GFAP Standard
- 10X Wash Buffer
- Buffer D
- Elution Buffer B
규격
Minimum of 4 plasma samples spiked with average recovery of 115% with a range of 110-119%
Minimum of 5 CSF samples spiked with average recovery of 101% with a range of 95-106%
법적 정보
면책조항
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
관련 콘텐츠
Discover how to expand neuroscience biomarker research with high sensitivity immunoassays, such as Single Molecule Counting (SMC®) assays. These assays give researchers the tools they need to detect low-abundant blood-based biomarkers and expand biomarker options in neuroscience research.
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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