N-145

Norbuprenorphine-D₉ solution

1 mg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant^®

• 실험식(Hill 표기법): C₂₅H₂₆D₉NO₄
• CAS Number: 1309388-84-8
• Molecular Weight: 422.61
• UNSPSC 코드: 41116107
• NACRES: NA.24

속성

• Grade: certified reference material
• Quality Level: 300
• 특징: Snap-N-Spike^®/Snap-N-Shoot^®
• 포장: ampule of 1 mL
• 제조업체/상표: Cerilliant^®
• 농도: 1 mg/mL in methanol
• 형식: single component solution
• 저장 온도: -10 to -25°C
• SMILES string: CC(O)(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])[C@](C1)([H])[C@@]([C@H]2[C@]([C@@]13[C@H]4C5)(CCN4)C6=C5C=CC(O)=C6O2)(CC3)OC

설명

애플리케이션

• Monitoring buprenorphine in treatment: Research highlighted the importance of monitoring buprenorphine and its metabolites, including norbuprenorphine, in patients undergoing medication-assisted treatment for opioid use disorder, emphasizing the utility of stable isotope-labeled standards like Norbuprenorphine-D₉ in mass spectrometry (Pesce et al., 2024).


• Method development in mass spectrometry: A study focused on the simplified processing and rapid quantification of buprenorphine, norbuprenorphine, and their conjugates in human plasma using UPLC-MS/MS. The research underlines the significance of deuterated standards such as Norbuprenorphine-D₉ for accurate internal referencing in analytical methods (Zhao et al., 2024).


• Substance detection in clinical settings: An investigation into the detection of buprenorphine, norbuprenorphine, and naloxone in adulterated urine samples addresses the forensic and clinical challenges in drug screening, where Norbuprenorphine-D₉ could serve as a critical analytical reference material (Furo et al., 2024).

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS02,GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H225,H301 + H311 + H331,H370
• 예방조치 성명서: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 표적 기관: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point (°F): 49.5 °F - closed cup
• Flash Point (°C): 9.7 °C - closed cup