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Merck
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Key Documents

N-006

Supelco

Normorphine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

실험식(Hill 표기법):
C16H17NO3
CAS Number:
Molecular Weight:
271.31
UNSPSC 코드:
41116107
NACRES:
NA.24

Grade

certified reference material

형태

liquid

특징

Snap-N-Spike®/Snap-N-Shoot®

포장

ampule of 1 mL

제조업체/상표

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

농도

1.0 mg/mL in methanol

기술

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

응용 분야

forensics and toxicology

형식

single component solution

저장 온도

2-8°C

SMILES string

O[C@H]1C=CC2[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3)c45

InChI

1S/C16H17NO3/c18-11-3-1-8-7-10-9-2-4-12(19)15-16(9,5-6-17-10)13(8)14(11)20-15/h1-4,9-10,12,15,17-19H,5-7H2/t9?,10-,12+,15+,16+/m1/s1

InChI key

ONBWJWYUHXVEJS-YTPBOXJFSA-N

일반 설명

Normorphine is a primary urinary metabolite of the opiate analgesic morphine. This Snap-N-Spike® reference solution is applicable for use in LC/MS or GC/MS applications such as pain prescription monitoring, urine drug testing, clinical toxicology, or forensic analysis. Morphine, used to relieve both acute and chronic severe pain is known under trade names MS Contin®, Kadian®, Oramorph®, and Roxanol.

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Kadian is a registered trademark of Actavis Elizabeth LLC
MS Contin is a registered trademark of Purdue Frederick Company
Oramorph is a registered trademark of AAIPharma, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

관련 제품

제품 번호
설명
가격

픽토그램

FlameSkull and crossbonesHealth hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

표적 기관

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point (°F)

49.5 °F - closed cup

Flash Point (°C)

9.7 °C - closed cup


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

D Wielbo et al.
Journal of chromatography, 615(1), 164-168 (1993-05-19)
An isocratic high-performance liquid chromatographic method has been developed for the determination of morphine, codeine, normorphine, morphine 3-glucuronide and morphine 6-glucuronide in plasma using a diol column and diode-array detection. Samples were extracted using solid-phase extraction with recoveries in excess
A M Evans et al.
The Journal of pharmacy and pharmacology, 47(4), 333-339 (1995-04-01)
A specific HPLC method with UV detection was used to investigate the disposition of morphine and its metabolites in the in-situ rat isolated perfused liver preparation. Livers of male Sprague-Dawley rats (n = 4) were perfused under single pass conditions
T A Aasmundstad et al.
Pharmacology & toxicology, 79(3), 114-119 (1996-09-01)
It has previously been shown that guinea pig hepatocytes metabolise morphine in a fashion similar to humans. The metabolism of morphine (5 muM) and the formation of metabolites morphine-3-glucuronide, morphine-6-glucuronide and normorphine was studied in the absence and presence of
D G Watson et al.
Journal of pharmaceutical and biomedical analysis, 13(1), 27-32 (1995-01-01)
A sensitive method for the analysis of unconjugated morphine, codeine, normorphine and total morphine after hydrolysis of glucuronide conjugates is described. The method was applicable to 50-microliters volumes of plasma. The analytes were converted to heptafluorobutyryl (HFB) derivatives before analysis
J Hasselström et al.
Clinical pharmacokinetics, 24(4), 344-354 (1993-04-01)
Morphine, morphine-6-glucuronide (M6G), morphine-3-glucuronide (M3G) and normorphine were analysed with high performance liquid chromatography in plasma and urine, collected over 72 h after administration of single intravenous 5 mg and oral 20 mg doses of morphine to 7 healthy volunteers.

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