D-010

1,2-Dinitroglycerin solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• 실험식(Hill 표기법): C₃H₆N₂O₇
• CAS Number: 621-65-8
• Molecular Weight: 182.09
• EC Number: 200-835-2
• MDL number: MFCD00661060
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329798580
• NACRES: NA.24

속성

• Grade: certified reference material
• 형태: liquid
• 특징: Snap-N-Spike^®/Snap-N-Shoot^®
• 포장: ampule of 1 mL
• 제조업체/상표: Cerilliant^®
• 농도: 1.0 mg/mL in acetonitrile
• 기술: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 응용 분야: pharmaceutical (small molecule)
• 형식: single component solution
• 저장 온도: −20°C
• SMILES string: OC[C@@H](O[N+]([O-])=O)CO[N+]([O-])=O
• InChI: 1S/C3H6N2O7/c6-1-3(12-5(9)10)2-11-4(7)8/h3,6H,1-2H2
• InChI key: GFVHBTOOPNJKLV-UHFFFAOYSA-N

설명

일반 설명

1,2-Dinitroglycerin is a major plasma metabolite of the pharmaceutical vasodilator nitroglycerin. This Certified Spiking Solution^® is suitable for use in chromatography or mass spectrometry-based applications in pharmaceutical research or clinical toxicology. Nitroglycerin is used to treat heart conditions such as angina and chronic heart failure.

애플리케이션

• Pharmacokinetics of transdermal nitroglycerin: Research demonstrates the pharmacokinetic profiling of nitroglycerin and its metabolites from a transdermal delivery system, including 1,2-Dinitroglycerin, which contributes to its sustained release and absorption characteristics. This study supports its use in controlled drug delivery applications (Auclair et al., 1998).



• Nitroglycerin metabolism research: Analytical techniques for studying the metabolism of nitroglycerin, including the role of 1,2-Dinitroglycerin, were detailed, highlighting methods for examining nitrite and glutathione interactions. This research aids in understanding the metabolic pathways and implications of nitroglycerin derivatives in pharmacology (Curry et al., 1987).

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS02,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H225,H302 + H312 + H332,H319
• 예방조치 성명서: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point (°F): 35.6 °F - closed cup
• Flash Point (°C): 2 °C - closed cup